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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for C5 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000187activation of MAPK activityTAS
GO:0001701in utero embryonic developmentIEA
GO:0002523leukocyte migration involved in inflammatory responseIEA
GO:0006874cellular calcium ion homeostasisIEA
GO:0006917induction of apoptosisIEA
GO:0006935chemotaxisTAS
GO:0006950response to stressTAS
GO:0006954inflammatory responseTAS
GO:0006956complement activationTAS
GO:0006957complement activation, alternative pathwayIEA
GO:0006958complement activation, classical pathwayIEA
GO:0007166cell surface receptor linked signaling pathwayTAS
GO:0007186G-protein coupled receptor protein signaling pathwayTAS
GO:0010575positive regulation vascular endothelial growth factor productionIDA
GO:0010700negative regulation of norepinephrine secretionIEA
GO:0010760negative regulation of macrophage chemotaxisIDA
GO:0019835cytolysisIEA
GO:0033602negative regulation of dopamine secretionIEA
GO:0042593glucose homeostasisIEA
GO:0045087innate immune responseTAS
GO:0045766positive regulation of angiogenesisIEA
GO:0050921positive regulation of chemotaxisIEA
GO:0090197positive regulation of chemokine secretionIDA
cellular_component
GO:0005576extracellular regionTAS
GO:0005579membrane attack complexIEA
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionIEA
molecular_function
GO:0004866endopeptidase inhibitor activityIEA
GO:0005102receptor bindingTAS
GO:0008009chemokine activityTAS
GO:0031714C5a anaphylatoxin chemotactic receptor bindingIEA

Protein-protein interaction details for C5 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
C6Co-fractionationphysical1387399
C6Reconstituted Complexphysical1387399
C7Reconstituted Complexphysical1387399
C8BReconstituted Complexphysical3624872
C5AR1Reconstituted Complexphysical9553099
CPB2Biochemical Activityphysical11939578
C6Reconstituted Complexphysical2808363
C3Reconstituted Complexphysical11367533