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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for WNT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000578 embryonic axis specification ISS GO:0001658 branching involved in ureteric bud morphogenesis IEA GO:0001934 positive regulation of protein phosphorylation IEA GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway IBA GO:0007267 cell-cell signaling ISS GO:0007275 multicellular organismal development IEA GO:0007520 myoblast fusion IEA GO:0008284 positive regulation of cell proliferation IDA GO:0008284 positive regulation of cell proliferation IMP GO:0009611 response to wounding IEP GO:0009798 axis specification IBA GO:0009880 embryonic pattern specification IBA GO:0010592 positive regulation of lamellipodium assembly IMP GO:0010812 negative regulation of cell-substrate adhesion IDA GO:0016055 Wnt receptor signaling pathway IDA GO:0021527 spinal cord association neuron differentiation IEA GO:0021536 diencephalon development IBA GO:0021551 central nervous system morphogenesis ISS GO:0021587 cerebellum morphogenesis IBA GO:0021588 cerebellum formation ISS GO:0021592 fourth ventricle development IBA GO:0021797 forebrain anterior/posterior pattern specification IBA GO:0022004 midbrain-hindbrain boundary maturation during brain development IBA GO:0022037 metencephalon development IEA GO:0022408 negative regulation of cell-cell adhesion IMP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA GO:0030579 ubiquitin-dependent SMAD protein catabolic process IEA GO:0030901 midbrain development IBA GO:0030901 midbrain development ISS GO:0030917 midbrain-hindbrain boundary development IEA GO:0031100 organ regeneration IEA GO:0033077 T cell differentiation in thymus IBA GO:0035284 brain segmentation IBA GO:0042472 inner ear morphogenesis IBA GO:0042770 signal transduction in response to DNA damage IDA GO:0043066 negative regulation of apoptosis IMP GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IDA GO:0044336 canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis IMP GO:0045599 negative regulation of fat cell differentiation IBA GO:0045599 negative regulation of fat cell differentiation ISS GO:0045747 positive regulation of Notch signaling pathway IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048146 positive regulation of fibroblast proliferation IMP GO:0048332 mesoderm morphogenesis IBA GO:0048664 neuron fate determination IBA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity ISS GO:0060061 Spemann organizer formation ISS GO:0060070 canonical Wnt receptor signaling pathway IMP GO:0061054 dermatome development IDA GO:0070365 hepatocyte differentiation IBA GO:0071375 cellular response to peptide hormone stimulus IEA GO:0071425 hemopoietic stem cell proliferation IBA GO:0090344 negative regulation of cell aging IDA GO:2000002 negative regulation of DNA damage checkpoint IDA GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process IEA cellular_component GO:0005576 extracellular region IEA GO:0005578 proteinaceous extracellular matrix IEA GO:0005615 extracellular space IBA GO:0005737 cytoplasm IDA GO:0005769 early endosome IBA GO:0005770 late endosome IBA GO:0005886 plasma membrane IBA GO:0009986 cell surface IEA GO:0045121 membrane raft IBA molecular_function GO:0005109 frizzled binding IC GO:0005110 frizzled-2 binding IBA GO:0005125 cytokine activity ISS GO:0005515 protein binding IPI GO:0019904 protein domain specific binding IEA GO:0044212 transcription regulatory region DNA binding IDA

Protein-protein interaction details for WNT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FZD8 Affinity Capture-Western physical 11448771 LRP6 Affinity Capture-Western physical 11448771 SFRP1 Affinity Capture-Western physical 10347172 WIF1 Affinity Capture-Western physical 19174556