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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAP3K12 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006468protein phosphorylationIDA
GO:0006468protein phosphorylationISS
GO:0006468protein phosphorylationTAS
GO:0007243intracellular protein kinase cascadeTAS
GO:0007254JNK cascadeISS
GO:0016572histone phosphorylationISS
GO:0018105peptidyl-serine phosphorylationISS
GO:0018107peptidyl-threonine phosphorylationISS
GO:0046777protein autophosphorylationISS
cellular_component
GO:0005624membrane fractionISS
GO:0005737cytoplasmIEA
GO:0005829cytosolISS
GO:0005886plasma membraneISS
GO:0030426growth coneIEA
GO:0033267axon partIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0000287magnesium ion bindingIEA
GO:0004672protein kinase activityTAS
GO:0004674protein serine/threonine kinase activityIEA
GO:0004674protein serine/threonine kinase activityISS
GO:0004709MAP kinase kinase kinase activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0019901protein kinase bindingIPI
GO:0042803protein homodimerization activityISS

Protein-protein interaction details for MAP3K12 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
FTLTwo-hybridphysical16169070
RGS1Two-hybridphysical16169070
TSC22D1Two-hybridphysical16169070
MAPK8IP1Affinity Capture-Westernphysical10490659
MAPK8IP2Affinity Capture-Westernphysical10490659
MAPK8IP1Reconstituted Complexphysical10490659
MAPK8IP2Reconstituted Complexphysical10490659
MBIPTwo-hybridphysical10801814
MBIPAffinity Capture-Westernphysical10801814
MAP2K7Biochemical Activityphysical10187804
MAP2K7Affinity Capture-Westernphysical10187804
EGFRPCAphysical20029029
EGFRAffinity Capture-Westernphysical20029029
MAPK6Two-hybridphysical21900206