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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EHMT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0006306 DNA methylation ISS GO:0009790 embryo development ISS GO:0016568 chromatin modification IDA GO:0016571 histone methylation IDA GO:0018026 peptidyl-lysine monomethylation ISS GO:0018027 peptidyl-lysine dimethylation IDA GO:0034968 histone lysine methylation IDA GO:0045892 negative regulation of transcription, DNA-dependent ISS GO:0051567 histone H3-K9 methylation ISS GO:0070734 histone H3-K27 methylation ISS cellular_component GO:0005634 nucleus IC GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005694 chromosome IEA molecular_function GO:0002039 p53 binding IPI GO:0008168 methyltransferase activity IDA GO:0008168 methyltransferase activity IEA GO:0008270 zinc ion binding IEA GO:0016279 protein-lysine N-methyltransferase activity IDA GO:0016740 transferase activity IEA GO:0018024 histone-lysine N-methyltransferase activity IDA GO:0018024 histone-lysine N-methyltransferase activity IEA GO:0046872 metal ion binding IEA GO:0046974 histone methyltransferase activity (H3-K9 specific) ISS GO:0046976 histone methyltransferase activity (H3-K27 specific) ISS

Protein-protein interaction details for EHMT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID JARID2 Affinity Capture-Western physical 19010785 HIST1H3A Co-crystal Structure physical 20084102 PCBD1 Two-hybrid physical 20211142 LZTR1 Two-hybrid physical 20211142 TRIM15 Two-hybrid physical 20211142 CTBP1 Affinity Capture-Western physical 16702210 CTBP2 Affinity Capture-Western physical 16702210 H3F3A Affinity Capture-MS physical 17403666 MDM2 Affinity Capture-Western physical 20588255 TP53 Biochemical Activity physical 20588255 HIST1H3A Biochemical Activity physical 20118233 TP53 Biochemical Activity physical 20118233 BCL6 Affinity Capture-MS physical 16147992 UBC Reconstituted Complex physical 19850743 HIST3H3 Biochemical Activity physical 12700765 CTBP1 Co-localization physical 12700765 SUMO1 Reconstituted Complex physical 19596686 UBC Affinity Capture-MS physical 21987572