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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NCK2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006417regulation of translationIEA
GO:0007015actin filament organizationIEA
GO:0007165signal transductionTAS
GO:0007172signal complex assemblyNAS
GO:0007173epidermal growth factor receptor signaling pathwayTAS
GO:0007176regulation of epidermal growth factor-activated receptor activityTAS
GO:0007411axon guidanceTAS
GO:0008285negative regulation of cell proliferationTAS
GO:0016477cell migrationIEA
GO:0030032lamellipodium assemblyIEA
GO:0030838positive regulation of actin filament polymerizationIMP
GO:0042102positive regulation of T cell proliferationIMP
GO:0042110T cell activationNAS
cellular_component
GO:0005737cytoplasmNAS
GO:0005783endoplasmic reticulumIEA
GO:0005829cytosolTAS
GO:0012506vesicle membraneIEA
molecular_function
GO:0005515protein bindingIPI
GO:0008093cytoskeletal adaptor activityNAS
GO:0030159receptor signaling complex scaffold activityNAS

Protein-protein interaction details for NCK2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ABI2Two-hybridphysical16189514
TRIP6Two-hybridphysical16189514
KIAA1217Two-hybridphysical16189514
NCKIPSDTwo-hybridphysical16189514
SF3B4Two-hybridphysical16189514
CBLBTwo-hybridphysical16189514
WBP11Two-hybridphysical16189514
CPSF6Two-hybridphysical16189514
FXR2Two-hybridphysical16189514
CPSF7Two-hybridphysical16189514
HNRNPKTwo-hybridphysical16189514
EEF1GTwo-hybridphysical16169070
EGFRReconstituted Complexphysical9737977
PDGFRBReconstituted Complexphysical9737977
DOK1Reconstituted Complexphysical9737977
DOCK1Reconstituted Complexphysical11240126
WIPF2Affinity Capture-Westernphysical12213210
PDGFRBReconstituted Complexphysical11027258
CD3EReconstituted Complexphysical12110186
CD3EReconstituted Complexphysical12110186
CD3ETwo-hybridphysical12110186
PTK2Reconstituted Complexphysical11950595
PTK2Affinity Capture-Westernphysical11950595
PAK1Affinity Capture-Westernphysical10026169
PKN2Affinity Capture-Westernphysical10026169
SOS1Affinity Capture-Westernphysical10026169
EGFRAffinity Capture-Westernphysical10026169
PDGFRBAffinity Capture-Westernphysical10026169
NTRK2Two-hybridphysical12074588
NTRK2Reconstituted Complexphysical12074588
LIMS1Reconstituted Complexphysical10022929
ILKReconstituted Complexphysical10022929
LIMS1Two-hybridphysical9843575
LIMS1Two-hybridphysical9843575
LIMS1Reconstituted Complexphysical9843575
EGFRAffinity Capture-Westernphysical9843575
IRS1Reconstituted Complexphysical9843575
MASP1Two-hybridphysical21900206