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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RUNX1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001501 skeletal system development IEA GO:0001701 in utero embryonic development IEA GO:0001889 liver development IEA GO:0006351 transcription, DNA-dependent IDA GO:0007417 central nervous system development IEA GO:0030097 hemopoiesis TAS GO:0030099 myeloid cell differentiation IDA GO:0030853 negative regulation of granulocyte differentiation IMP GO:0030854 positive regulation of granulocyte differentiation IMP GO:0035162 embryonic hemopoiesis IEA GO:0045766 positive regulation of angiogenesis ISS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0048266 behavioral response to pain IEA GO:0048666 neuron development IEA GO:0048935 peripheral nervous system neuron development TAS GO:0060216 definitive hemopoiesis IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus TAS GO:0005730 nucleolus IDA GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0003677 DNA binding IDA GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005509 calcium ion binding IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding NAS GO:0008134 transcription factor binding IDA GO:0042803 protein homodimerization activity IDA GO:0046982 protein heterodimerization activity IDA GO:0070491 repressing transcription factor binding IEA

Protein-protein interaction details for RUNX1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SUV39H1 Affinity Capture-Western physical 12917624 SUV39H1 Reconstituted Complex physical 12917624 MYST4 Affinity Capture-Western physical 11965546 CBFB Co-crystal Structure physical 10856244 AES Two-hybrid physical 10825294 PAX5 Reconstituted Complex physical 10455134 YAP1 Two-hybrid physical 10228168 JUN Reconstituted Complex physical 11274169 FOS Reconstituted Complex physical 11274169 JUN Affinity Capture-Western physical 11274169 FOS Affinity Capture-Western physical 11274169 SMAD3 Affinity Capture-Western physical 10531362 SMAD1 Affinity Capture-Western physical 10531362 SMAD2 Affinity Capture-Western physical 10531362 SMAD5 Affinity Capture-Western physical 10531362 VDR Reconstituted Complex physical 12460926 VDR Affinity Capture-Western physical 12460926 JUN Reconstituted Complex physical 11641401 FOS Reconstituted Complex physical 11641401 ELF4 Affinity Capture-Western physical 10207087 ELF4 Reconstituted Complex physical 10207087 ETS1 Reconstituted Complex physical 10207087 ELF2 Reconstituted Complex physical 10207087 EFNA2 Reconstituted Complex physical 10207087 CEBPB Reconstituted Complex physical 8622667 TLE1 Two-hybrid physical 9751710 TLE1 Far Western physical 9751710 CBFA2T2 Affinity Capture-Western physical 9447981 TRAF6 Affinity Capture-Western physical 18768464 FHL2 Affinity Capture-Western physical 18768464 MYOD1 Affinity Capture-Western physical 20195544 CBFB Affinity Capture-Western physical 20195544 MYOD1 Reconstituted Complex physical 20195544 UBC Affinity Capture-Western physical 16046550 HIPK2 Affinity Capture-Western physical 16917507 HIPK2 Affinity Capture-Western physical 16917507 HIPK2 Biochemical Activity physical 16917507 EP300 Affinity Capture-Western physical 16917507 SUV39H1 Affinity Capture-Western physical 16652147 SUV39H1 Co-purification physical 16652147 HDAC1 Affinity Capture-Western physical 16652147 HDAC3 Affinity Capture-Western physical 16652147 MYST3 Affinity Capture-MS physical 11742995 CBFB Affinity Capture-MS physical 11742995 MYST3 Affinity Capture-Western physical 11742995 MYST3 Affinity Capture-Western physical 11742995 MYST3 Biochemical Activity physical 11742995 TCF12 Affinity Capture-Western physical 15333839 TCF3 Affinity Capture-Western physical 15333839 RUNX1T1 Co-purification physical 10882117 NCOR1 Reconstituted Complex physical 10882117 SIAH1 Affinity Capture-Western physical 18073335 UBE2L6 Reconstituted Complex physical 18073335 RUNX1 Affinity Capture-Western physical 18073335 SIAH1 Affinity Capture-Western physical 18073335 PML Affinity Capture-Western physical 18073335 RARA Affinity Capture-Western physical 18073335 HDAC2 Affinity Capture-Western physical 18073335 SIN3A Affinity Capture-Western physical 14729951 SIN3A Affinity Capture-Western physical 14729951 CBFB Affinity Capture-Western physical 14729951 NR4A2 Affinity Capture-Western physical 21468021 NR4A2 Affinity Capture-Western physical 21468021 TRIM33 Affinity Capture-MS physical 20603019 STUB1 Affinity Capture-Western physical 19524548 STUB1 Reconstituted Complex physical 19524548 STUB1 Affinity Capture-Western physical 19524548 UBC Affinity Capture-Western physical 19524548 SMARCA4 Affinity Capture-Western physical 20506188 SMARCB1 Affinity Capture-Western physical 20506188 SMARCC1 Affinity Capture-Western physical 20506188 SMARCA4 Affinity Capture-Western physical 20506188 SMARCB1 Affinity Capture-Western physical 20506188 HDAC1 Affinity Capture-Western physical 21059642 HDAC3 Affinity Capture-Western physical 21059642 HDAC1 Affinity Capture-Western physical 21059642 HDAC3 Affinity Capture-Western physical 21059642 HDAC1 Reconstituted Complex physical 21059642 HDAC3 Reconstituted Complex physical 21059642 CDK1 Biochemical Activity physical 21059642 TAL1 Affinity Capture-MS physical 19497860