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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BECN1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000045 autophagic vacuole assembly IEA GO:0000910 cytokinesis IMP GO:0006914 autophagy IEA GO:0006916 anti-apoptosis TAS GO:0006968 cellular defense response TAS GO:0007049 cell cycle IEA GO:0008285 negative regulation of cell proliferation IEA GO:0009615 response to virus IEA GO:0016239 positive regulation of macroautophagy IEA GO:0051707 response to other organism IEA cellular_component GO:0005737 cytoplasm IEA GO:0005794 Golgi apparatus IEA GO:0005802 trans-Golgi network IEA GO:0016020 membrane IEA GO:0016023 cytoplasmic membrane-bounded vesicle IEA GO:0043234 protein complex IEA molecular_function GO:0005515 protein binding IPI

Protein-protein interaction details for BECN1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCL2 Two-hybrid physical 9765397 GOPC Two-hybrid physical 12372286 GOPC Reconstituted Complex physical 12372286 GOPC Affinity Capture-Western physical 12372286 BCL2 FRET physical 9765397 BCL2L1 Two-hybrid physical 9765397 TSC1 Affinity Capture-MS physical 20562859 PIK3C3 Affinity Capture-MS physical 20562859 PIK3R4 Affinity Capture-MS physical 20562859 SLC27A4 Affinity Capture-MS physical 20562859 UVRAG Affinity Capture-MS physical 20562859 DZIP3 Affinity Capture-MS physical 20562859 PTOV1 Affinity Capture-MS physical 20562859 TBC1D7 Affinity Capture-MS physical 20562859 ATG14 Affinity Capture-MS physical 20562859 KIAA0226 Affinity Capture-MS physical 20562859 TRABD Affinity Capture-MS physical 20562859 NRBF2 Affinity Capture-MS physical 20562859 TP53BP2 Affinity Capture-MS physical 20562859 AMBRA1 Affinity Capture-MS physical 20562859 GSPT1 Affinity Capture-MS physical 20562859 AFG3L2 Affinity Capture-MS physical 20562859 SEH1L Affinity Capture-MS physical 20562859 PRKDC Affinity Capture-MS physical 20562859 C13orf18 Affinity Capture-MS physical 20562859 ZWINT Affinity Capture-MS physical 20562859 SMC1A Affinity Capture-MS physical 20562859 SMC3 Affinity Capture-MS physical 20562859 ATG14 Affinity Capture-MS physical 20562859 PIK3C3 Affinity Capture-MS physical 20562859 UVRAG Affinity Capture-MS physical 20562859 BCL2 Affinity Capture-Western physical 20889974 UBC Affinity Capture-Western physical 20501938 TRAF6 Affinity Capture-Western physical 20501938 TRAF6 Biochemical Activity physical 20501938 UBC Reconstituted Complex physical 20501938 TNFAIP3 Affinity Capture-Western physical 20501938 BECN1 Affinity Capture-Western physical 20501938 HSP90AA1 Affinity Capture-Western physical 21543763 BCL2 Affinity Capture-Western physical 21543763