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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AIFM1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006309 DNA fragmentation involved in apoptotic nuclear change IEA GO:0006919 activation of caspase activity IDA GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis TAS GO:0045454 cell redox homeostasis IEA GO:0051402 neuron apoptosis IEA GO:0070059 apoptosis in response to endoplasmic reticulum stress IEA GO:0070059 apoptosis in response to endoplasmic reticulum stress ISS cellular_component GO:0005625 soluble fraction IEA GO:0005634 nucleus IEA GO:0005634 nucleus ISS GO:0005737 cytoplasm IEA GO:0005739 mitochondrion IEA GO:0005743 mitochondrial inner membrane IEA GO:0005758 mitochondrial intermembrane space IDA GO:0005792 microsome IEA GO:0005829 cytosol IEA GO:0005829 cytosol ISS GO:0016020 membrane IEA GO:0048471 perinuclear region of cytoplasm IEA molecular_function GO:0003677 DNA binding IEA GO:0005515 protein binding IPI GO:0009055 electron carrier activity TAS GO:0016491 oxidoreductase activity IEA GO:0050660 flavin adenine dinucleotide binding IEA

Protein-protein interaction details for AIFM1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PELO Affinity Capture-MS physical 17353931 MLF2 Affinity Capture-MS physical 17353931 C20orf24 Affinity Capture-MS physical 17353931 PTP4A3 Affinity Capture-MS physical 17353931 BRF2 Affinity Capture-MS physical 17353931 HSPA1A Affinity Capture-Western physical 12930708 SETDB1 Two-hybrid physical 16169070 STC2 Two-hybrid physical 16169070 HSPA1A Affinity Capture-Western physical 11533664 XIAP Affinity Capture-Western physical 17967870 XIAP Affinity Capture-Western physical 17967870 UBC Affinity Capture-Western physical 17967870 MLH1 Affinity Capture-MS physical 17148452 PMS2 Affinity Capture-MS physical 17148452 UBASH3A Affinity Capture-Western physical 17709377 ENDOG Affinity Capture-Western physical 16133872 H2AFX Affinity Capture-MS physical 20000738 RYK Affinity Capture-MS physical 21875946 SPG20 Affinity Capture-MS physical 19765186 TUBA3E Affinity Capture-MS physical 20360068 XIAP Biochemical Activity physical 22103349 UBC Affinity Capture-Western physical 22103349 AMFR Affinity Capture-MS physical 21343306 UBC Affinity Capture-MS physical 18781797 LRDD Affinity Capture-MS physical 21415862