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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACVR2A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001934 positive regulation of protein phosphorylation IMP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway TAS GO:0007368 determination of left/right symmetry IEA GO:0007498 mesoderm development IEA GO:0009952 anterior/posterior pattern specification IEA GO:0010033 response to organic substance IEA GO:0030501 positive regulation of bone mineralization IMP GO:0030509 BMP signaling pathway IDA GO:0030509 BMP signaling pathway IMP GO:0030509 BMP signaling pathway TAS GO:0030510 regulation of BMP signaling pathway IEA GO:0032924 activin receptor signaling pathway IEA GO:0032927 positive regulation of activin receptor signaling pathway IDA GO:0042713 sperm ejaculation IEA GO:0043084 penile erection IEA GO:0045648 positive regulation of erythrocyte differentiation IDA GO:0045669 positive regulation of osteoblast differentiation IMP GO:0046881 positive regulation of follicle-stimulating hormone secretion IEA GO:0048706 embryonic skeletal system development IEA GO:0050999 regulation of nitric-oxide synthase activity IEA GO:0060011 Sertoli cell proliferation IEA cellular_component GO:0005737 cytoplasm IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0016020 membrane IEA GO:0034673 inhibin-betaglycan-ActRII complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004675 transmembrane receptor protein serine/threonine kinase activity TAS GO:0004702 receptor signaling protein serine/threonine kinase activity IEA GO:0004872 receptor activity IEA GO:0005024 transforming growth factor beta-activated receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0015026 coreceptor activity IDA GO:0016362 activin receptor activity, type II IEA GO:0016362 activin receptor activity, type II TAS GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0017002 activin-activated receptor activity IDA GO:0019838 growth factor binding IEA GO:0043621 protein self-association IEA GO:0046872 metal ion binding IEA GO:0048185 activin binding IEA GO:0048185 activin binding IPI GO:0048186 inhibin beta-A binding IDA GO:0048186 inhibin beta-A binding IEA GO:0048187 inhibin beta-B binding IEA

Protein-protein interaction details for ACVR2A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SYNJ2BP Two-hybrid physical 15451561 INHBA Affinity Capture-Western physical 10746731 INHA Affinity Capture-Western physical 10746731 GDF5 Affinity Capture-Western physical 8702914 ENG Affinity Capture-Western physical 9872992 INHBB Affinity Capture-Western physical 9202237 INHBA Affinity Capture-Western physical 9202237 BMP6 Affinity Capture-Western physical 10504300 ACVR1B Affinity Capture-Western physical 9892009 BMP7 Affinity Capture-Western physical 9748228 ACVR1B Affinity Capture-Western physical 8612709 SYNJ2BP Reconstituted Complex physical 11882656 SYNJ2BP Two-hybrid physical 11882656 MAGI2 Two-hybrid physical 15451561