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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MTDH (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0010508positive regulation of autophagyIDA
GO:0031663lipopolysaccharide-mediated signaling pathwayIMP
GO:0043066negative regulation of apoptosisIDA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0045766positive regulation of angiogenesisIDA
GO:0051092positive regulation of NF-kappaB transcription factor activityIDA
GO:0051897positive regulation of protein kinase B signaling cascadeIDA
GO:0070830tight junction assemblyIEA
cellular_component
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005783endoplasmic reticulumIDA
GO:0005789endoplasmic reticulum membraneISS
GO:0005923tight junctionISS
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0016324apical plasma membraneISS
GO:0016604nuclear bodyIDA
GO:0030054cell junctionIEA
GO:0031965nuclear membraneIEA
GO:0046581intercellular canaliculusISS
GO:0048471perinuclear region of cytoplasmIDA
molecular_function
GO:0001085RNA polymerase II transcription factor bindingIPI
GO:0003713transcription coactivator activityIMP
GO:0005515protein bindingIPI
GO:0051059NF-kappaB bindingIPI

Protein-protein interaction details for MTDH (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
OTUD6BAffinity Capture-MSphysical19615732
SUMO1Affinity Capture-Westernphysical19383828
UBCAffinity Capture-Westernphysical19383828
MMEAffinity Capture-MSphysical17342744