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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BRE (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006302 double-strand break repair IMP GO:0006915 apoptosis IEA GO:0006974 response to DNA damage stimulus IEP GO:0007165 signal transduction TAS GO:0010212 response to ionizing radiation IMP GO:0016568 chromatin modification IEA GO:0031572 G2/M transition DNA damage checkpoint IMP GO:0045739 positive regulation of DNA repair IMP GO:0045768 positive regulation of anti-apoptosis IDA cellular_component GO:0000152 nuclear ubiquitin ligase complex IDA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0070531 BRCA1-A complex IDA GO:0070552 BRISC complex IDA molecular_function GO:0000268 peroxisome targeting sequence binding TAS GO:0005164 tumor necrosis factor receptor binding IDA GO:0005164 tumor necrosis factor receptor binding IEA GO:0005515 protein binding IPI GO:0031593 polyubiquitin binding IDA

Protein-protein interaction details for BRE (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID C19orf62 Two-hybrid physical 16189514 C19orf62 Affinity Capture-MS physical 17353931 BRCC3 Affinity Capture-MS physical 17353931 FAM175B Affinity Capture-MS physical 17353931 BARD1 Affinity Capture-MS physical 14636569 BARD1 Affinity Capture-Western physical 14636569 BRCA1 Affinity Capture-MS physical 14636569 BRCA1 Affinity Capture-Western physical 14636569 BRCA1 Co-purification physical 14636569 BRCA2 Affinity Capture-MS physical 14636569 BRCA2 Co-purification physical 14636569 BRCA2 Affinity Capture-Western physical 14636569 BRCC3 Affinity Capture-MS physical 14636569 BRCC3 Affinity Capture-Western physical 14636569 RAD51 Affinity Capture-MS physical 14636569 RAD51 Affinity Capture-Western physical 14636569 RAD51 Co-purification physical 14636569 TP53 Affinity Capture-MS physical 14636569 TP53 Affinity Capture-Western physical 14636569 TP53 Co-purification physical 14636569 BRCC3 Co-purification physical 14636569 UBE2D1 Reconstituted Complex physical 14636569 UIMC1 Affinity Capture-MS physical 17525341 PHB Affinity Capture-MS physical 19615732 RPN2 Affinity Capture-MS physical 19615732 SHMT2 Affinity Capture-MS physical 19615732 SSR3 Affinity Capture-MS physical 19615732 BRCC3 Affinity Capture-MS physical 19615732 USP7 Affinity Capture-MS physical 19615732 C19orf62 Affinity Capture-MS physical 19615732 UIMC1 Affinity Capture-MS physical 19615732 LRPPRC Affinity Capture-MS physical 19615732 SLC25A13 Affinity Capture-MS physical 19615732 ATG2A Affinity Capture-MS physical 19615732 FAM175B Affinity Capture-MS physical 19615732 TTC28 Affinity Capture-MS physical 19615732 FKBP8 Affinity Capture-MS physical 19615732 DHRS7B Affinity Capture-MS physical 19615732 C19orf62 Affinity Capture-MS physical 19615732 UIMC1 Affinity Capture-MS physical 19615732 TMX3 Affinity Capture-MS physical 19615732 UGGT2 Affinity Capture-MS physical 19615732 MMS19 Affinity Capture-MS physical 19615732 BRCC3 Affinity Capture-MS physical 19615732 FAM175A Affinity Capture-MS physical 19615732 TNFRSF1A Affinity Capture-Western physical 15465831 FAS Affinity Capture-Western physical 15465831 TNFRSF1A Affinity Capture-Western physical 15465831 FAS Affinity Capture-Western physical 15465831 SUMO1 Affinity Capture-Western physical 15465831 UBC Affinity Capture-Western physical 15465831 COPS5 Affinity Capture-Western physical 19214193 NCOA3 Two-hybrid physical 21577200 UBC Affinity Capture-MS physical 16196087 C19orf62 Affinity Capture-Western physical 19261749 FAM175A Affinity Capture-MS physical 19261749 FAM175A Affinity Capture-Western physical 19261749 UIMC1 Affinity Capture-Western physical 19261749 UIMC1 Affinity Capture-Western physical 19261749 FAM175A Affinity Capture-Western physical 19261749 BRCC3 Affinity Capture-Western physical 19261749 C19orf62 Affinity Capture-Western physical 19261749 BRCC3 Affinity Capture-Western physical 19261749 UBC Reconstituted Complex physical 19261749 C19orf62 Affinity Capture-MS physical 19261746 FAM175A Reconstituted Complex physical 19261746 UIMC1 Reconstituted Complex physical 19261746 C19orf62 Reconstituted Complex physical 19261746 BRCC3 Reconstituted Complex physical 19261746 BRCC3 Reconstituted Complex physical 20032457 FAM175B Affinity Capture-Western physical 21282113 FAM175A Affinity Capture-Western physical 21282113 C19orf62 Affinity Capture-Western physical 21282113 C19orf62 Reconstituted Complex physical 21282113 UIMC1 Affinity Capture-Western physical 21282113 FAM175A Affinity Capture-Western physical 21282113 FAM175B Affinity Capture-Western physical 21282113 BRCC3 Affinity Capture-Western physical 21282113 C19orf62 Affinity Capture-Western physical 21282113 BRCC3 Affinity Capture-Western physical 21282113 BRCC3 Affinity Capture-Western physical 20656689 UIMC1 Affinity Capture-Western physical 20656689 FAM175A Affinity Capture-Western physical 20656689 C19orf62 Affinity Capture-Western physical 20656689 BRCC3 Affinity Capture-Western physical 20656689 UIMC1 Affinity Capture-MS physical 19261748 FAM175A Affinity Capture-MS physical 19261748 BRCC3 Affinity Capture-MS physical 19261748 C19orf62 Affinity Capture-MS physical 19261748 UIMC1 Affinity Capture-MS physical 19261748 FAM175A Affinity Capture-MS physical 19261748 C19orf62 Affinity Capture-MS physical 19261748 BRCC3 Affinity Capture-MS physical 19261748 C19orf62 Affinity Capture-Western physical 19261748 C19orf62 Affinity Capture-Western physical 19261748 FAM175A Affinity Capture-Western physical 19261748 BRCC3 Affinity Capture-Western physical 19261748 FAM175A Affinity Capture-Western physical 19261748 UIMC1 Affinity Capture-Western physical 19261748 FAM175A Reconstituted Complex physical 19261748 C19orf62 Reconstituted Complex physical 19261748 UIMC1 Affinity Capture-Western physical 19261748 UIMC1 Reconstituted Complex physical 19261748 UBC Affinity Capture-MS physical 21987572