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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RAPGEF2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000165 MAPKKK cascade NAS GO:0007264 small GTPase mediated signal transduction IEA GO:0007264 small GTPase mediated signal transduction TAS GO:0019933 cAMP-mediated signaling NAS GO:0032854 positive regulation of Rap GTPase activity IDA GO:0035556 intracellular signal transduction TAS GO:0051056 regulation of small GTPase mediated signal transduction IEA cellular_component GO:0005622 intracellular IEA GO:0005622 intracellular TAS GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane NAS GO:0016020 membrane IDA molecular_function GO:0004871 signal transducer activity TAS GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005509 calcium ion binding NAS GO:0017034 Rap guanyl-nucleotide exchange factor activity IDA GO:0019992 diacylglycerol binding NAS GO:0046582 Rap GTPase activator activity IDA

Protein-protein interaction details for RAPGEF2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RALGDS Two-hybrid physical 7809086 RALGDS Reconstituted Complex physical 7809086 RAP1A Biochemical Activity physical 10934204 RAP1A Reconstituted Complex physical 10934204 RAP2B Reconstituted Complex physical 10934204 HSPA1A Two-hybrid physical 20936779 KIF5A Two-hybrid physical 20936779 KIF5B Two-hybrid physical 20936779 ATP8 Two-hybrid physical 20936779 MOBKL3 Two-hybrid physical 20936779 NEDD4 Affinity Capture-Western physical 11598133 UBC Affinity Capture-Western physical 11598133 NEDD4 Reconstituted Complex physical 11598133 PRKCI Affinity Capture-MS physical 14676191