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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GAB2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IDA GO:0008284 positive regulation of cell proliferation IDA GO:0030316 osteoclast differentiation IMP GO:0043306 positive regulation of mast cell degranulation ISS GO:0048015 phosphatidylinositol-mediated signaling ISS cellular_component GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA molecular_function GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity IDA GO:0005070 SH3/SH2 adaptor activity RCA GO:0005515 protein binding IPI GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding ISS GO:0043325 phosphatidylinositol-3,4-bisphosphate binding ISS

Protein-protein interaction details for GAB2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCR Affinity Capture-Western physical 15143164 GRB2 Affinity Capture-Western physical 15143164 ETV6 Affinity Capture-Western physical 15143164 ARHGAP32 Two-hybrid physical 12819203 ARHGAP32 Affinity Capture-Western physical 12819203 LYN Affinity Capture-Western physical 11971018 PLCG2 Affinity Capture-Western physical 12135708 PTPN11 Affinity Capture-Western physical 12135708 PLCG2 Affinity Capture-Western physical 12135708 PTPN11 Affinity Capture-Western physical 12135708 SHC1 Affinity Capture-Western physical 12135708 ZAP70 Affinity Capture-Western physical 11572860 CD247 Affinity Capture-Western physical 11572860 LAT Affinity Capture-Western physical 11572860 PTPN6 Affinity Capture-Western physical 11895767 SHC1 Affinity Capture-Western physical 11782427 PTPN11 Affinity Capture-Western physical 11782427 GRB2 Affinity Capture-Western physical 11782427 PIK3R1 Affinity Capture-Western physical 11782427 AKT1 Affinity Capture-Western physical 11782427 AKT1 Biochemical Activity physical 11782427 PTPN11 Affinity Capture-Western physical 10391903 GRB2 Affinity Capture-Western physical 10391903 GRB2 Reconstituted Complex physical 10391903 GRAP Reconstituted Complex physical 10391903 SRC Affinity Capture-Western physical 10391903 NCK1 Reconstituted Complex physical 10391903 PLCG1 Reconstituted Complex physical 10391903 PIK3R1 Affinity Capture-Western physical 11334882 PTPN11 Affinity Capture-Western physical 11334882 CRKL Affinity Capture-Western physical 11334882 PIK3R1 Two-hybrid physical 11334882 PTPN11 Two-hybrid physical 11334882 CRKL Two-hybrid physical 11334882 CRKL Protein-peptide physical 11334882 MET Affinity Capture-Western physical 10871282 CRKL Affinity Capture-Western physical 10871282 PTPN11 Affinity Capture-Western physical 10871282 PIK3R1 Affinity Capture-Western physical 10871282 GRB2 Two-hybrid physical 20936779