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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CASP8AP2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006919 activation of caspase activity ISS GO:0007049 cell cycle IEA GO:0007165 signal transduction TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0008625 induction of apoptosis via death domain receptors ISS GO:0071260 cellular response to mechanical stimulus IEP cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA molecular_function GO:0003714 transcription corepressor activity IDA GO:0005123 death receptor binding TAS GO:0005515 protein binding IPI GO:0008656 caspase activator activity ISS GO:0016505 apoptotic protease activator activity ISS

Protein-protein interaction details for CASP8AP2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRAF2 Reconstituted Complex physical 11340079 TRAF2 Affinity Capture-Western physical 11340079 CASP8AP2 Affinity Capture-Western physical 10235259 FADD Affinity Capture-Western physical 10235259 FAS Affinity Capture-Western physical 10235259 CASP8 Affinity Capture-Western physical 10235259 UBE2I Two-hybrid physical 20936779 GLUL Two-hybrid physical 20936779 SREBF2 Two-hybrid physical 20936779 CALM1 Reconstituted Complex physical 15840729 UBC Affinity Capture-MS physical 17370265