Species |
Homo sapiens |
Tissue |
uterus;;Endometrium;;Secretory (Luteal);;Mid (Receptive) |
Condition |
Chemical treatment;;GnRH agonist |
|
VS |
Species |
Homo sapiens |
Tissue |
uterus;;Endometrium;;Secretory (Luteal);;Mid (Receptive) |
Condition |
Chemical treatment;;GnRH antagonist |
|
Top 10 Top 100 All genes References |
Up-regulated |
Genes |
Score |
GO annotation |
|
Down-regulated |
Genes |
Score |
GO annotation |
CXCL1 |
2 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
- actin cytoskeleton organization
- cell proliferation
- chemotaxis
more... - immune response
- inflammatory response
- intracellular signal transduction
- negative regulation of cell proliferation
- nervous system development
- positive regulation of catalytic activity
- signal transduction
less...
|
| cellular_component | - extracellular region
- extracellular space
- intracellular
|
| molecular_function | - chemokine activity
- enzyme activator activity
- growth factor activity
- receptor binding
more...
|
| |
HBEGF |
2 |
BP MF CC |
biological_process | - epidermal growth factor receptor signaling pathway
- muscle organ development
- negative regulation of elastin biosynthetic process
- positive regulation of cell growth
more... - positive regulation of cell migration
- positive regulation of keratinocyte migration
- positive regulation of protein kinase B signaling cascade
- positive regulation of smooth muscle cell proliferation
- positive regulation of wound healing
- regulation of heart contraction
- signal transduction
- wound healing, spreading of epidermal cells
less...
|
| cellular_component | - cell surface
- extracellular region
- extracellular space
- integral to plasma membrane
more... - plasma membrane
less...
|
| molecular_function | - epidermal growth factor receptor binding
- eukaryotic cell surface binding
- growth factor activity
- heparin binding
more... - receptor activity
less...
|
| |
IGFBP5 |
2 |
BP MF CC |
biological_process | - cellular response to cAMP
- cellular response to organic cyclic compound
- glucose homeostasis
- glucose metabolic process
more... - hair follicle morphogenesis
- intracellular signal transduction
- mammary gland involution
- negative regulation of cell migration
- negative regulation of insulin-like growth factor receptor signaling pathway
- negative regulation of smooth muscle cell migration
- negative regulation of smooth muscle cell proliferation
- negative regulation of translation
- osteoblast differentiation
- positive regulation of protein kinase B signaling cascade
- regulation of cell growth
- signal transduction
- skeletal muscle tissue growth
- striated muscle cell differentiation
less...
|
| cellular_component | - extracellular region
- insulin-like growth factor binding protein complex
|
| molecular_function | - fibronectin binding
- insulin-like growth factor I binding
- insulin-like growth factor binding
- protein binding
more...
|
| |
|
Up-regulated |
Genes |
Score |
GO annotation |
|
Down-regulated |
Genes |
Score |
GO annotation |
CXCL1 |
2 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
- actin cytoskeleton organization
- cell proliferation
- chemotaxis
more... - immune response
- inflammatory response
- intracellular signal transduction
- negative regulation of cell proliferation
- nervous system development
- positive regulation of catalytic activity
- signal transduction
less...
|
| cellular_component | - extracellular region
- extracellular space
- intracellular
|
| molecular_function | - chemokine activity
- enzyme activator activity
- growth factor activity
- receptor binding
more...
|
| |
HBEGF |
2 |
BP MF CC |
biological_process | - epidermal growth factor receptor signaling pathway
- muscle organ development
- negative regulation of elastin biosynthetic process
- positive regulation of cell growth
more... - positive regulation of cell migration
- positive regulation of keratinocyte migration
- positive regulation of protein kinase B signaling cascade
- positive regulation of smooth muscle cell proliferation
- positive regulation of wound healing
- regulation of heart contraction
- signal transduction
- wound healing, spreading of epidermal cells
less...
|
| cellular_component | - cell surface
- extracellular region
- extracellular space
- integral to plasma membrane
more... - plasma membrane
less...
|
| molecular_function | - epidermal growth factor receptor binding
- eukaryotic cell surface binding
- growth factor activity
- heparin binding
more... - receptor activity
less...
|
| |
IGFBP5 |
2 |
BP MF CC |
biological_process | - cellular response to cAMP
- cellular response to organic cyclic compound
- glucose homeostasis
- glucose metabolic process
more... - hair follicle morphogenesis
- intracellular signal transduction
- mammary gland involution
- negative regulation of cell migration
- negative regulation of insulin-like growth factor receptor signaling pathway
- negative regulation of smooth muscle cell migration
- negative regulation of smooth muscle cell proliferation
- negative regulation of translation
- osteoblast differentiation
- positive regulation of protein kinase B signaling cascade
- regulation of cell growth
- signal transduction
- skeletal muscle tissue growth
- striated muscle cell differentiation
less...
|
| cellular_component | - extracellular region
- insulin-like growth factor binding protein complex
|
| molecular_function | - fibronectin binding
- insulin-like growth factor I binding
- insulin-like growth factor binding
- protein binding
more...
|
| |
|
|
|
Identifiers | Repository | Data-sets |
20042535 | PubMed | 1 | |
Up-regulated(0) Down-regulated(3) |