Entrez gene ID | | 10 |
Official gene symbol | | NAT2 |
Full name | | N-acetyltransferase 2 (arylamine N-acetyltransferase) |
Aliases | | ,AAC2,PNAT, |
Gene summary | | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p22 |
Gene position | | 18248755 - 18258723 Map Viewer |
Gene orientation | | plus |
Gene size | | 9969 bp |
Gene sequence |
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OMIM ID | | 612182 |
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