Entrez gene ID | | 10016 |
Official gene symbol | | PDCD6 |
Full name | | programmed cell death 6 |
Aliases | | ,ALG-2,FLJ46208,MGC111017,MGC119050,MGC9123,PEF1B, |
Gene summary | | This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5p15.33 |
Gene position | | 271736 - 315089 Map Viewer |
Gene orientation | | plus |
Gene size | | 43354 bp |
Gene sequence |
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OMIM ID | | 601057 |
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