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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDH4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1002
Official gene symbolCDH4
Full namecadherin 4, type 1, R-cadherin (retinal)
Aliases,CAD4,FLJ22202,FLJ40547,MGC126700,MGC138355,RCAD,
Gene summaryThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.3
Gene position59827559 - 60512299  Map Viewer
Gene orientationplus
Gene size684741 bp
Gene sequence
OMIM ID603006