Entrez gene ID | | 10054 |
Official gene symbol | | UBA2 |
Full name | | ubiquitin-like modifier activating enzyme 2 |
Aliases | | ,ARX,FLJ13058,HRIHFB2115,SAE2, |
Gene summary | | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q12 |
Gene position | | 34919268 - 34960798 Map Viewer |
Gene orientation | | plus |
Gene size | | 41531 bp |
Gene sequence |
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OMIM ID | | 613295 |