Entrez gene ID | | 1009 |
Official gene symbol | | CDH11 |
Full name | | cadherin 11, type 2, OB-cadherin (osteoblast) |
Aliases | | ,CAD11,CDHOB,OB,OSF-4, |
Gene summary | | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q22.1 |
Gene position | | 65155919 - 64980683 Map Viewer |
Gene orientation | | minus |
Gene size | | 175237 bp |
Gene sequence |
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OMIM ID | | 600023 |
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