Entrez gene ID | | 1010 |
Official gene symbol | | CDH12 |
Full name | | cadherin 12, type 2 (N-cadherin 2) |
Aliases | | ,CDHB,FLJ34857, |
Gene summary | | This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5p14-p13 |
Gene position | | 22853731 - 21750973 Map Viewer |
Gene orientation | | minus |
Gene size | | 1102759 bp |
Gene sequence |
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OMIM ID | | 600562 |
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