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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDH12 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1010
Official gene symbolCDH12
Full namecadherin 12, type 2 (N-cadherin 2)
Aliases,CDHB,FLJ34857,
Gene summaryThis gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq]
LocationChromosome: 5   Locus: 5p14-p13
Gene position22853731 - 21750973  Map Viewer
Gene orientationminus
Gene size1102759 bp
Gene sequence
OMIM ID600562