Entrez gene ID | | 10105 |
Official gene symbol | | PPIF |
Full name | | peptidylprolyl isomerase F |
Aliases | | ,CYP3,Cyp-D,FLJ90798,MGC117207, |
Gene summary | | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q22-q23 |
Gene position | | 81107220 - 81115090 Map Viewer |
Gene orientation | | plus |
Gene size | | 7871 bp |
Gene sequence |
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OMIM ID | | 604486 |