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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACTR1A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10121
Official gene symbolACTR1A
Full nameARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
Aliases,ARP1,CTRN1,FLJ52695,FLJ52800,FLJ55002,
Gene summaryThis gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q24.32
Gene position104262512 - 104238986  Map Viewer
Gene orientationminus
Gene size23527 bp
Gene sequence
OMIM ID605143