Entrez gene ID | | 10121 |
Official gene symbol | | ACTR1A |
Full name | | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
Aliases | | ,ARP1,CTRN1,FLJ52695,FLJ52800,FLJ55002, |
Gene summary | | This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q24.32 |
Gene position | | 104262512 - 104238986 Map Viewer |
Gene orientation | | minus |
Gene size | | 23527 bp |
Gene sequence |
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OMIM ID | | 605143 |
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