Entrez gene ID | | 1016 |
Official gene symbol | | CDH18 |
Full name | | cadherin 18, type 2 |
Aliases | | ,CDH14,CDH14L,CDH24, |
Gene summary | | This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5p15.2-p15.1 |
Gene position | | 19988353 - 19473140 Map Viewer |
Gene orientation | | minus |
Gene size | | 515214 bp |
Gene sequence |
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OMIM ID | | 603019 |
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