Entrez gene ID | | 10215 |
Official gene symbol | | OLIG2 |
Full name | | oligodendrocyte lineage transcription factor 2 |
Aliases | | ,BHLHB1,OLIGO2,PRKCBP2,RACK17,bHLHe19, |
Gene summary | | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.11 |
Gene position | | 34398239 - 34401500 Map Viewer |
Gene orientation | | plus |
Gene size | | 3262 bp |
Gene sequence |
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OMIM ID | | 606386 |