Entrez gene ID | | 10269 |
Official gene symbol | | ZMPSTE24 |
Full name | | zinc metallopeptidase (STE24 homolog, S. cerevisiae) |
Aliases | | ,FACE-1,FACE1,FLJ14968,HGPS,PRO1,STE24,Ste24p, |
Gene summary | | This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p34 |
Gene position | | 40723733 - 40759856 Map Viewer |
Gene orientation | | plus |
Gene size | | 36124 bp |
Gene sequence |
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OMIM ID | | 606480 |