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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for APBB3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10307 Official gene symbol APBB3 Full name amyloid beta (A4) precursor protein-binding, family B, member 3 Aliases ,FE65L2,MGC150555,MGC87674,SRA, Gene summary The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 5   Locus: 5q31 Gene position 139944189 - 139937853  Map Viewer Gene orientation minus Gene size 6337 bp Gene sequence >APBB3:complement(1100780..1107116):Length=6337 CGCGGCGCATGTTCGGCGTGTCGGTCTTCAGGCGCCTGATGAGTTCATAGTTGGGCGGTG GTGTCAGCGGTTTCGCTGGCGTTCGTGGGCCTCCCCCGGACCCACACACGGAAACACGCA ACCATTCGGGGATCCAGACGCCCGTTTACACGCACCACCCCTGGGCGGGCTGTGCGGCTC AGGCCCTCCCCCGGGACCGGCCCGTGTCCCGCCCCGTGTCCCGCCCCGTATTTGTGCGGC GCCAGCTGGCCCCGCAGCCTGCGGCGCAGAGAGGCTGGGCTTGCAGGCGCAGTAGCTCCA GAGGTCGCGCTGGGCTGAGAGTGCGGGCCGGCAGAGGCTGGCGGGGAGCAGCCGGGGTTA TGCTGGGCAAGGATTACATGCTGGCCATCATTCTGGTCAACTGCGATGGTGTGCACGGAG GGGCCCGGTGGGAAGACCAGGAGCTGAGGGAGGACGAGGGAATCCGAAAGGCTACTCTGG GGCTCAAAGACGGTGGGGGATACCTCTCTGTGTAGGGACCAGGGGGCGAATGAACCCGGT CTTTACATGTGATGTCTTCAAGATTGAGGAGCCTGGATCTTCAGCCTAAGAACTGACCCA TTTTGGGGATGGAGAGGGGATTATGACAGCATGTTATTCTGAACTCACAAATCATATGCT CCCTCCTCTCTAATCCGGTGTTCCTGTAGATGACTTGTGGGGGGACCACAGTCTGGAGGT GGAGGCTGGCCTGCCTCCTGGCTGGAGGAAGATCCACGATGCTGCAGGTACTTACTACTG GCATGTACCCAGCGGTAGCACCCAGTGGCAGCGCCCAACCTGGGAACTAGGAGATGCAGA GGACCCAGGCACGGTAGGTAGAGTGTGAGGAGGAGGTCTGAGCCCATGTGTGGACCTAGG TCTGCTGTTAAACTGACTAACTCCCACTCTACAGGGAACGGAGGGGATCTGGGGACTGCG GCCCCCCAAAGGGAGATCCTTCTCCAGCCTGGAGAGTTCACTGGACCGGAGGTAACGGGT GGCCCAGGCAAAATGAAAGGCTTGGGGTTCCATGGTGTTCAAAAATGCAGCTGGACCCAT GGTCTGCTTTCCAGCCCAGGTTCTGGATTCTGTCACATGTTTTGGGTTCTGTTACGTTCT TGGCTCTGTCCCAGGTTCTTAACTGTCAGTATTTTGAGTTTTATCCCTTGTTCTAAGCTC TTGTTTGTAGCTACATGTTTTTCATATTCTTGGTCCTAACCTATCATGTTCTAGACCTTG GCCATTAAGTCCTCTGTTCTAGGGTCTCTTGTCCCACTTTGGGGTTCTGGTCCACATATT GGACCCTGTTCTATTTTGTGACTTTTATTTTTTATTTTTTGAGATGGAGTCTCACTCTGT CATCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTGCAACCTCCGCCTCCCAGGTT CAAGTCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAAACTACAGGCACATGCCACCATG CCCAGCTAATGTTTGTATTTTTAGTAGATATGGGGTTTCACCATGTTGGCCAGGATGGTC TCGATATCCTGACCTCATGATCCACCCGTCTCAGCCTCCCAAAGTGTTGGGATTACAGGC GTGAGCCACCACTGCACCTAGCCTTGTGACTTTTATTCTATGTCCTGTGTCTGGGTCCTA TGTCCTGAATTTTCCCTCAAATTCTGAGTCACACTTTATGTTACGTTAATATGTCCTGGG CTCTACCCTGCTCTGGTTTTATATTTCTGGTGCTATATTCTGGGTCTTGCCCCTCATCCT GTGCTTATCAAGTTGTCTAGGCCTCACCAGTGTCCCTACTGTAGGAAATGTGGTCCTCTT AACAGCTCTGCTCTGTTTCAGTAACTCTCTGTCCTGGTATGGTGGGGAATCCTACATCCA GAGCATGGAGCCAGGGGCTAAGGTAGTGACTTGGGCCTGAGGGCATTGGGAGGTCCCAAG GGAAAGACAAGGGTGGGATTGGACTGAACAGAGGTGATCAAGGGTGAAGACAGGGAGTAT GTATTGTGGCACCTGCCACCCTACTCCATCCTTATTAATTCCTGTCCCTTCCCCCAACCT GTCAGTGCTTTGCAGTCCGCTCTCTGGGCTGGGTAGAGGTACCTGAAGAGGACCTGGCAC CGGGGAAGAGCAGTATTGCAGTCAATAACTGTATCCAGCAGCTGGCCCAGACCCGCAGCC GGAGCCAGCCTCCAGATGGTGCCTGGGGTGAGGTGAGTTGGCTGGGCCCTTTAATGGTTT GGGCCCAGGGCCCAGCAGAGGTAGCTGTCCCTGAATTTCCTATTTCTCATGGCAATGACC TTTATCTGAGCTCTGGGCTGACCTCTGTCCTTGGCAGGGCCAGAACATGCTGATGATCCT GAAGAAGGATGCCATGAGCCTAGTGAATCCCCTGGACCACAGTCTGATCCACTGCCAGCC TCTGGTGCACATCCGTGTGTGGGGCGTGGGGAGCTCCAAGGGCCGGTGAGGATGCCTACA TCCCCCAAGCAAGAGCTACTTCTCCCTCCCGGCTGCAGGCTGTGATCCCCACTGATGCTG ATCCCCAGTACTTGAACCCCTGGACACAGATCCTCTGATGTGGACCCAGGACTGCTTCCC CTGCCTGGTCCAGCCCTGGTTGGGGAGGGTGGGCCCAGCTCAGCAGGGACAGTTTGGGGA GAGTCCGAGAGGCTGGGCTGATTCCCTTCTGTGCTCCCACATGCTTCCGGAACAGTGACA GGTGAGTGAAAACCAGGTATCCTGAGCCCCATCCCTGATGTCCCTACTCCATCCCTGCTA TATCCCTAGCCTGACTTTCCAGCCTCCTGCAGGCTCCTGCCTCTAACCAGCTTCTACCCC AGCCCCATCTCTGCCCCTGCTAGGGACTTCGCTTTTGTGGCAAGTGACAAAGATAGCTGT ATGCTCAAGTGCCATGTGTTTTGCTGTGATGTCCCTGCCAAGGCCATTGCCAGTGCCCTA CATGGGCTTTGTGCCCAGGTAAGTGTCAGGGGTGGGGCAGGGAATGTGGGTAAGGGGTTG GGTCTGAAGCTTCCAAGGTAGTTGGGGTGGTATTGGCCCTTTTACCCTAATTCCCCTCTC TCCCTGTGGGTCATGCTGGCTTCATTGTGTTTTAGATCTTGTCAGAGCGAGTAGAGGTCA GTGGTGATGCCTCTTGCTGCTCCCCAGACCCCATCTCTCCTGAAGACCTGCCACGGCAAG GTATGGGGAGGGGAGACCTGCATTGCTGCATTGGGGTGCTTTGGTGCTGCTTTGTGGGGG GGCGATTTCTGGTTATTTAATACTTCTGTGGATAAATTTCTGAGATGTCTGGTCTCAGGG ATCCCAAGCCACTAGTTGGAGGAGCATCTATGAGCCATTTCTTCTACCAGCACCAGCTCT GACCTGAGTCCTGGCCCATTGAGAAGGGTGGGGAAAAGGGTAATTGAAAGAGCTTCCAGG CCAACTTGGTGTGTATATTTCAGTGGAGCTGCTGGATGCGGTAAGCCAAGCTGCTCAGAA GTACGAGGCACTGTATATGGGGACACTGCCAGTCACCAAGGCCATGGGTGAGGACTGAGG GGGCTGCATGTGGTGGGCTGTGTGAGGCAAGGGGAAGGTGAGTGAGGTGAGGCCTGTTAT CATTTCTCAAGAGTCCTCCCGTGGCCTTGTTATGGCCTGGGGTCTACCAGCCTTCCCAAA TCAGAATTCTAAGGCTTGCCCCAGCTATCCTATTCCCTATCTCTGAATCCCAAATCAGTG AGAGGGGGCTAGACACTCCCTGCAGACTCTTTCTTTTACACTGGGAGACACGCTGGGTAT GTTCCCCCAGGCATGGATGTGCTGAACGAGGCCATTGGTACCCTCACCGCCAGGGGGGAC CGGAATGCCTGGGTCCCCACCATGCTCAGTGTGTCTGACTCTCTCATGACTGCACACCCC ATTCAGGTACCAGAAGAGGGTGAAGTTGGGGGCTTTGGAGGGGTGAGCAGGGATGCTGAG GGGTCACTGCTTGCTGTCGGAAAAGTTAAGTGGGTCTGGCCCGTGCTTGGCCCTCTAGTG ACTAGGCCTGGTGTGGGCAGGCAGAGGCCAGTACAGAGGAGGAGCCATTGTGGCAGTGCC CTGTGCGCCTTGTGACATTTATTGGTGTTGGCCGCGACCCACACACCTTTGGCCTCATCG CTGACCTGGGCCGTCAGAGCTTCCAGTGCGCAGCCTTCTGGTGCCAGCCCCATGCAGGGG GACTCTCTGAAGCTGTGCAGGCTGCCTGTATGGTGAGTCATGGGTGGGAATGGGTTGGTG GGATTGCCCTGCAGCTGCTCTCCACTGTTTACTTGGGCTCCGGGTCGGCAGCCTCTTCAG AGATCACAAACCTGGGCTGATTCTGGTTCATTAATGTTTTGGCCCTCATGTTGTTTTTAG TAAGTTTTAATTAGTTGCCAATATTTAAAGGCCAGGACATTTCACATAATAATCGCTATT CTTGTTTTTCTTAAAATATCAAGAGCTCTGGCACTCAGTTCACACGTGTAAGTGTCAGCA TGCAGCCAGAGTTGTGCAGAAGCTGTGCCCTAAAGAGTTGGCATTGTTCCTGTTTGTCTC ATTTAGGTTTATTTCCTGGCATCTGTGGGCATTTGAGTGTGGGTTGCTTATACTTCGTTA GTTCAGTTTGCCCATTCATTCAACAAATATGGGTGCCTACAGGGTCCCAGACACCATAGC TGACCCTGAGAATTTAGTGCTGTAGAGGGCACAGCCCTTGCCTTCACAAAACACTTAGGA TAGAGCCAAGATAGACCAGAAATAAGTTGTACACCACTGGTTGATGGAAGAGGTGGCCCC TTTAGGGGTCAGGAAGGCTACCTGTAAGAGGTGATAGAAATCCGACAGTCCAAGAGGGAA GTTAGCCAGGTGAAGGGGAGTGGGGCAGGTGTACCAAGCACAGGGAACCTTAGCTGTGAA GGTGAGAGATATTAGTGGATGAGAGTATCTGAAAGAATCTAGTGTATCTGGCATGCAAGG GGGACGTAGTGAGAGGTGAGATCAGAGAGAATGACAGAAGCCAGGTTTGGGGGACCTCAT AGGTCAGGGTGATGAGTTTATCTGGAGGCACTAGGAAGCACTGGAGCCCGAGAGTGAAGT CAGGGTTATGGATTAGGATGACCACTTAAGCTATAGTATGGGTAAAAGATTTGGAGGACG TAATAGGAGGTAGGAAGGCCAATTAGGACACCTTTGAGCTGTTCAGATGAGATGACTGGG AGCAGTTGCATTGGGGCTGGAGTTTGAGTTGTACACCTTTACCCTTGACTAGGGAATCTG CTTTGCCAGGGACTAGTCCCCACCAGTGAGAGATGGAAAAGAGGCAACATAGTGGTACAT GTAATTAAGAGTTTAGGCTCTGCAATCAGAGAGAACTAGGTTTGAATGCCATTTCTGCCT TTCTCTGGCTGTGTGACCTTGGGCAAGTCATATACTCTCTGAATCTCAATTTCCTCTTTT GCAAAACAGGGATAATAACCCCTCATAAATAACTGAATTATACAAAGCACTTAGCAGTGT CCAGCCTGCCCTCCTTAAGTGTCTGATACATGTTTTATGATTTTGTTATTGAGCTACCTG GGAATGCTCTAGAAACTCCACATGTGGCTGACTACCAACCTTGTTATCAGACAGAAGCTT TGGCCAGTTCCCTGTCCTGCAGAAGCTTTCAGGGAGTCTAGAGGCAGAAAGTAGCTGGAT CCTCACATTCCCCTTCTCCCTAGGTTCAGTACCAGAAGTGTCTTGTGGCCTCTGCAGCTC GAGGCAAGGCCTGGGGTGCCCAGGCCCGTGCCCGCCTGCGGCTCAAGCGGACCAGCTCCA TGGATTCCCCAGGAGGTCCCCTGCCCCTCCCCCTGCTCAAAGGAGGGGTTGGCGGTGCAG GGGCAACCCCTCGAAAGCGGGGTGTCTTCTCTTTTCTTGATGCCTTCCGGCTGAAACCCT CTCTGCTCCATATGCCCTAAACTTATCTGGGAAGGCTGGGGAAGTAGGCTCTGGGTCCAT GCCTAACTCTGTACCGTTTTATTCCTCAAGGCCTATAGCCTGTCACTCCTTGAAGCCTTC TCTGCCTGTCCCTCCGATCCTTGTCCACCGTCTATTTATTGCCCAATTTATTGTTTATAC GGATGACTGGGAGGCACTGCACCACAACGTAGGACCCTGGCTCCCCTTTCCTTGGGTCCT TGTGTTCCTTGCCCCTGTCCAACCCTGGACAGTTGGCTCTACCTCAGTAACACTTTATAG CAAAATCAGTGCAAATAAAAATCCCTCAGTGACCTCA OMIM ID 602711