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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDKN2D (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1032 Official gene symbol CDKN2D Full name cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) Aliases ,INK4D,p19,p19-INK4D, Gene summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13 Gene position 10679655 - 10677138  Map Viewer Gene orientation minus Gene size 2518 bp Gene sequence >CDKN2D:complement(1939940..1942457):Length=2518 AGAGCAGACCCCGCCCGGCGAGGAGGAGGGAGGGTGAGTTAGGGGGAGACCCGGCCCCCA AGGGGCGGGCGCCGGGCAGGGCCCCGCGGGCGGCCGAGGGTTGGGCCCGGCTCCCAGCCC CTCGCCGTCCTCCGGCTGACAGGGGGAGGAGCCCGCCGGGAGGGCCGGGGTCTCGGGCTG GGGAGCCGGGACGGGAGAGCAGCGCAGCCGGGTGCACCGCGGCCGCGCCCCGGGAGGGCT GTTCGGGCCAGCGCCCGCCGGCTGCTCCGCGCTGACAGCGCCGGGCTGGGGCGGGGCGGG GGGCTTTGCAGGCCGCCAGTGTCGACATGCTGCTGGAGGAGGTTCGCGCCGGCGACCGGC TGAGTGGGGCGGCGGCCCGGGGCGACGTGCAGGAGGTGCGCCGCCTTCTGCACCGGGAGC TGGTGCATCCCGACGCCCTCAACCGCTTCGGCAAGACGGCGCTGCAGGTGAGGCCGGGCC GGTCCAGGTTGGGGCGGGGCGGCTAAGCGGGATGAGGATCGAGACCCCAGAGCTCCTCTC TGGTCTCCTGGCCCTGGTGGTGACCCACTGGGAACCGGTCCTTCTTCTCTAGGCTTTCAT TGTTCCCCCACAGTCCCCCTTCGAAGGTGGGTGGTGGGTGAGGCTAGGTTGTGGGGGGAG GGGAGAGCTTTTTAGCATCTTCTCTGGGAGGATTCCTGGTTCTCTGAGTGCCGGGGATTC ACTTTCCCTGGGGAGGTTCTTATTCCGTGGGTGCGGGTTCAGCTCCTTTGGATGCCGTTT CCATGGGGACGGCTCACGTTTCTTGGGGCTTCTATGGGGAGATCCGATCTCTGGAAGGAG AGGTCCTGTCTCTAGGGGTTCCTCATTTTGTAGGGGGCTCTCTGAGACAAATCTGGTTAC TTGGGGGTGGGGTCTTCATTCCTAAAGGTTATGCGGATCCTTGATATAGTATGGGGGCCC CAATGGAGGAACAATGTCAGATTGCAAGACATCCCTATATTCCCTGGGAGACATTTTACA GGGAAGTCTCGTTTCTCTTTTATTATTACTTTTGGAATCCCGCTTCTTGAAAGGAGCTCT CAGGTACTCTGAGGTGACATCACCATTATGTAGGAGGAGGCTATTTCCTGGAGAAGGGGT TCGCTTTCCTTTGACATCTTTTTTCCCTTATGAGGACTATCAATTCTTTGGGGGTAGTTC TCCATCTCTGGGGGCCCATTTCCTGGAGGGGATTTTCTGTTTCCTGGTGATTGCCCATAT CTGGGGGCGTCTTTGGTCCCTTGGGGGAGAGTCTTAGGTTCCTTGAAAGTTTCCATGGGG GGCTGTTCTCTGGGTTGGGGGGTCTCATTCTTAAGGGAGTGACCAGCTTTTGGGGGGGGT CCCTATTCCCAGAAGAACTTTCCTGGGGGCTTATGCAGCTTCTCCGTTCACTAGAGGACC CCTCCTCTAGCATTTCCTGTTTCTGGGAGATGCCTCTTTCTGGATGACCCTTCTCTTTCC AGTGACCCCTTTTGTGGAACCTCCTCCCTTGAGGACCTCCTGATCCTCTGTCCCTCACAC AGGTCATGATGTTTGGCAGCACCGCCATCGCCCTGGAGCTGCTGAAGCAAGGTGCCAGCC CCAATGTCCAGGACACCTCCGGTACCAGTCCAGTCCATGACGCAGCCCGCACTGGATTCC TGGACACCCTGAAGGTCCTAGTGGAGCACGGGGCTGATGTCAACGTGCCTGATGGCACCG GGGCACTTCCAATCCATCTGGCAGTTCAAGAGGGTCACACTGCTGTGGTCAGCTTTCTGG CAGCTGAATCTGATCTCCATCGCAGGGACGCCAGGGGTCTCACACCCTTGGAGCTGGCAC TGCAGAGAGGGGCTCAGGACCTCGTGGACATCCTGCAGGGCCACATGGTGGCCCCGCTGT GATCTGGGGTCACCCTCTCCAGCAAGAGAACCCCGTGGGGTTATGTATCAGAAGAGAGGG GAAGAAACACTTTCTCTTCTTGTTTCTCCTGCCCACTGCTGCAGTAGGGGAGGAGCACAG TTTGTGGCTTATAGGTGTTGGTTTTGGGGGTGTGAGTGTTTGGGGGACGTTTCTCATTTG TTTTTCTCACTCCTTTTGGTGTGTTGGACAGAGAAGGGCTCCTGCAGGCCACAGCCACCT AAACGGTTCAGTTTCTTCTGCGCCTCAGGCTGCTGGGGCCTCAGACGAGACCCAAGGGCA GAGCATTTAAGAGTGAAGTCATGACCTCCAGGGAGCCTAGAAGCTGGTGGCCTTGGCCGG CTGTGCTCAGAGACCTGAAGTGTGCACGTTGCTTCAGGCATGGGGGGTGGGGGGAGCGTC CCAAATCAATAAGAAGGTAGAATGAGTTATGAGTTATTCATATTCTGTTGGAAGCTTGTT TTCCAGTCTCTTGTACAGCGTTTTAAAAGAAATGGATTCTATTTATTATGCTTTATTGGA AAAAATGTTGTAATAATTTAATGTTTTTACCCATTAAATTAAGACTTGTGCATGATCA OMIM ID 600927