Entrez gene ID | | 10346 |
Official gene symbol | | TRIM22 |
Full name | | tripartite motif-containing 22 |
Aliases | | ,GPSTAF50,RNF94,STAF50, |
Gene summary | | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15 |
Gene position | | 5710919 - 5732093 Map Viewer |
Gene orientation | | plus |
Gene size | | 21175 bp |
Gene sequence |
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OMIM ID | | 606559 |
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