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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BPNT1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10380
Official gene symbolBPNT1
Full name3'(2'), 5'-bisphosphate nucleotidase 1
Aliases,PIP,
Gene summaryBPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q41
Gene position220263191 - 220230824  Map Viewer
Gene orientationminus
Gene size32368 bp
Gene sequence
OMIM ID604053