| Entrez gene ID | | 10458 |
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| Official gene symbol | | BAIAP2 |
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| Full name | | BAI1-associated protein 2 |
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| Aliases | | ,BAP2,FLAF3,IRSP53, |
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| Gene summary | | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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| Location | | Chromosome: 17 Locus: 17q25 |
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| Gene position | | 79008947 - 79091232 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 82286 bp |
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| Gene sequence |
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| OMIM ID | | 605475 |
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