Entrez gene ID | | 1051 |
Official gene symbol | | CEBPB |
Full name | | CCAAT/enhancer binding protein (C/EBP), beta |
Aliases | | ,C/EBP-beta,CRP2,IL6DBP,LAP,MGC32080,NF-IL6,TCF5, |
Gene summary | | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.1 |
Gene position | | 48807376 - 48809212 Map Viewer |
Gene orientation | | plus |
Gene size | | 1837 bp |
Gene sequence |
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OMIM ID | | 189965 |
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