Entrez gene ID | | 10521 |
Official gene symbol | | DDX17 |
Full name | | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 |
Aliases | | ,DKFZp761H2016,P72,RH70, |
Gene summary | | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.1 |
Gene position | | 38902345 - 38879443 Map Viewer |
Gene orientation | | minus |
Gene size | | 22903 bp |
Gene sequence |
| |
OMIM ID | | 608469 |
|