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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CEL (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1056
Official gene symbolCEL
Full namecarboxyl ester lipase (bile salt-stimulated lipase)
Aliases,BAL,BSDL,BSSL,CELL,CEase,FAP,FAPP,LIPA,MODY8,
Gene summaryThe protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.3
Gene position135937365 - 135947248  Map Viewer
Gene orientationplus
Gene size9884 bp
Gene sequence
OMIM ID114840