Entrez gene ID | | 1058 |
Official gene symbol | | CENPA |
Full name | | centromere protein A |
Aliases | | ,CENP-A, |
Gene summary | | Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p24-p21 |
Gene position | | 27008882 - 27017457 Map Viewer |
Gene orientation | | plus |
Gene size | | 8576 bp |
Gene sequence |
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OMIM ID | | 117139 |