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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TXNRD2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10587
Official gene symbolTXNRD2
Full namethioredoxin reductase 2
Aliases,SELZ,TR,TR-BETA,TR3,TRXR2,
Gene summaryThioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.21
Gene position19929359 - 19863040  Map Viewer
Gene orientationminus
Gene size66320 bp
Gene sequence
OMIM ID606448