Entrez gene ID | | 10602 |
Official gene symbol | | CDC42EP3 |
Full name | | CDC42 effector protein (Rho GTPase binding) 3 |
Aliases | | ,BORG2,CEP3,FLJ46903,UB1, |
Gene summary | | CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p21 |
Gene position | | 37899326 - 37870743 Map Viewer |
Gene orientation | | minus |
Gene size | | 28584 bp |
Gene sequence |
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OMIM ID | | 606133 |
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