Entrez gene ID | | 10608 |
Official gene symbol | | MXD4 |
Full name | | MAX dimerization protein 4 |
Aliases | | ,MAD4,MST149,MSTP149,bHLHc12, |
Gene summary | | This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p16.3 |
Gene position | | 2263739 - 2249160 Map Viewer |
Gene orientation | | minus |
Gene size | | 14580 bp |
Gene sequence |
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