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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CENPF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1063
Official gene symbolCENPF
Full namecentromere protein F, 350/400ka (mitosin)
Aliases,CENF,PRO1779,hcp-1,
Gene summaryThis gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32-q41
Gene position214776532 - 214837914  Map Viewer
Gene orientationplus
Gene size61383 bp
Gene sequence
OMIM ID600236