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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CES1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1066 Official gene symbol CES1 Full name carboxylesterase 1 (monocyte/macrophage serine esterase 1) Aliases ,ACAT,CEH,CES2,HMSE,HMSE1,MGC117365,PCE-1,SES1,TGH, Gene summary This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 16   Locus: 16q13-q22.1 Gene position 55867075 - 55836763  Map Viewer Gene orientation minus Gene size 30313 bp Gene sequence >CES1:complement(26724..57068):Length=30345 AGCGCAGGGCGGTAACTCTGGGCGGGGCTGGGCGCCAGGGCTGGACAGCACAGTCCCTCT GAGCTGCACGGAGACCTCGCAGGCCCCCGGAACTGTCGCCCTTCCAGGATGTGGCTCCCT GCTCTTGTCCTGGCCACTCTCGCTGCTTCCGCGGCTTGGGGTGAGTCCTTCTGAAGTCAA ATATGCGGGGCACTTTTTGAAATCCTTGTTCTGGGCCGAGGTGGGCGCAGATGCGTAGAA AGGCAAAGACACAACAGGTCCGGCTCTGCGGCGGGGCACGACTTCCATATTAGGACTTGG ACTTGGAGCAGCTGAGCCCGGCCAGCCTGGCCCGCGCGGAGACGCAGGGAGGGTGAACAT CCTGAGATCGCCCTGTACTGCTCGCCCAAATGCAGGCCGACAGCCGGCCCACCTCAGGCC GCACACACGAGAAATTTAGGCAGCTCAGTTTGCTGTCCCTTAATTAGTCCCCTTACGGCT GGATCACGGAGAGCGGCTCAACATAATATTAAGAGCATCGACTCTGGAGCCAGAGTGCGT GGGTTCGAGTCCCCGCTGGGCGCTTCCTCGCTGTGTGTCCTTAGGCAAGGGACTGCGCTA TTCCGTGCTTGGGTTACCCCCTCTCTGAAACAGAGGTGGCAGTGCTGCCTACCTCACTGG GCTTTGGTGAGGAGGAAATGGGTGGCTGTTTCTAAAGCACTCTTGGCAGCGCCTGGTATG TAGAAAGCACGAAAAAGGGATGGATAAATAAAGGCGCTGTTTAAAAACGTAGTGTATGAA TAGAAAATTTGAGCTGTGGTCAGGCCACTATATCAGGACCTCTTGCCATTAAAAAGACAG TTTCTTACTCATGTTCTCAACAGGAGGGGGACACCAGTGCGCGGGGCACAAGGGGAAGCA GCAGAGCCTGGGGAGGGGACAGGGCGGATCTGAGGCCAAGGGGCTTTTACTGTGGCTTCC AAGGATAGAAGAGGAAAGGCAGGGCAGGCAGGCTGAGGACTGGCAAGTTGGGATACTTCA GGGGCTCTGGGGCACAGGGGCTGTTCCTAATTGTTTTGTACCTAGCCCTGGCATGATTAG GGCAGGTGGGTAGTGGCCAGGGCATGGCAACCCGATCAAAGAGGCGGTTGGAGTGTGGGC TCCAGGTTGGCTGGACCCTGGGAGGGACAGTTTCTCCAAGGTCAACAAGGCCTCAGATGC CAGAACATCAGAATACAGAAAGCAAAACAGATGGTACATAGAGGGGTGCAGCGAGGGGCC TCGAAATACCCCCGTGCCATTTTATAGACAGAGAAACTGAGACTCACACAGGGAAATGTA CTTGCCCAGGGTCAACCCGAAAATCACGCCTAGGTCTGTCTCTGGGTCCTGAATCCTGAC AGCCCAGCCCCGTCTGCATCCTGTCTTCCTTCTGGCAGCCTGACACTGCGAGAGCTCTGG AACTGTGGGGAAGGGCAGAGAAGAGAGGAAGCCTATTTGGAACTGAATGTTCCTTTACCT CTGGTTACTCCTGGCAATGCCATCCATTTCCTTCCTTAGGAAGACCATACAGGCTGCCTC CACTTCCTCAGTTTCCTCCTCTGTAAAATGGGCATGTTGATGCCTACCCAGCAAGGCTTA TTTGAAGATGGATTTAAACAAACTGGAATGCATGCCTGGCACATAGTAGGTGCCCACCAT GTTCGTGCTTCATATAACATCAGCAGCAACTGGTCTTGTTCTCACACTTGTTTCTGCCTC CCCCCATTCACCCACTTTTTCACCCTTGGCAATCTGGCTGCCATCCACCTCATCCTGTTG AAGGGAATCCCTGAGCTGAGCATGACCAGCCCAGTGGTTTCTTCTCTGACTTGACTCTCC TCCACCTCCCTGAAGTCCTCAGCAATCTTAGCTGGTTCCTCGCCCTCTTGCTCCCTGGGC TTCAAAGACATGGGAACGTTCTCTCTCCCCTATTCTGATGGATCTTTGGTCTTGGCCGTA GTGGTCCCTGTGTTTGACCTTTGTTTTTTTTTCTCTTCCCTCTCACACTGGCATCTTCAA TGAAGCCATACACATCCACCGTATGTACCCTCACAGTCCAGGAGAAGATTCTGCCCTGCT CCCTCACCAGGCTTCCTTCCAGCTTTGAAGTGCGCTCATCCTGTGGCATCATCTTGCCTG GATATCCCACTCACATCTCCACCGAGCCTGTGTAAACAGGGATCCAGCATTACAAGCCAG CTCTTTGGTCTTCTTTCCCTTCCATTTCCCCCACCTCTGGTCAGGGACCAAGTCTTTTCT TTTCCTTTCTTTTCTTTCCCTCCCTCCCTCACTCCCACTTGCCTGCCTGCCTGCCTGCCT GCCTGCCTGCCTGCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT TCCTTCCTTCCTTCTTTCCTTCCTTCCTTCTTTCCTTCCTTCCTTCCATCCTTCCATCTT TCCTTTCCTTCTTTCCTTCTTCTCTCTCTCTGGAGGAGCCAGGATTACAGGCTCATGCTA CCACACCCAGCTAATTTTTCTATTTTCAGTAGAGAGGGGGTTTCACCATGTTGGCCAGGC TGGTCTTGAACTCCTGACCTCAAATGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGAT TACAGGTGATCCACTGTGCCTGGTCTCCAAGTCTTTCAAAATACCTTTTAGACATCATCA TATTTCTACATATTTTTTCTTTTTTTATTTAAAATTTTAAAATAATTAAGATGGGGGGGA GGATTTCAGGTGAAGACCGGAAATCCCATACAGTGCTGAAAAGGTGGAAATCACCAAGAA AACAGGCCACATGTAATGCCACCACCCATTGCTATGTCGATAAACATGCTTCCAAGGAAG TTCATCTCAGTATTATTTGTAATTAGCAACAACAACAAAAGAAAAGAAGCTAAATATTGA CATTGCAGGGTTGGCTATTAATAAGATGAGACATGGATGCTGTTGTGTAACTGGGCTTTC CATAATGGGTTTCCATTGTGATTGGATATTCCCCTTTAAGACCAAATCTGAATTGTTCTG TTCTGCTCTAGCCCCACACTTTGAGGGAGGTGTTGACGTCTTGTCTGTATCCAAAGCAGA GCAGCTGGGAGGACAAGAGGCTGGAAATCATTTCCTAGGAGGGAAGCTCAGAGAAACTGA GGTGACTGGAGCCAGATAGGACCTGAGGGGTGGGCAGCAAGATCAAGTGTCTGAAAGGCC ACAGGCTGCAGATCAGATCAGGCCAGTATAGTCCCATGACAGGTAGAACCAGAACTGATG CGGAGGCTGTGGGAAATGAATTTCAGCTCAGTGAGGAAACATTGTCCGTGCTGCAAGAAT GGAGCAGACCTGCCCAGGGCCACCAGAAGAATCTTCCTTGACCTGATCACATCCTTTATC TGGAACGGTTCCTGCTGCTTATTTGTCCATTAAAGAAAACTCAAGCGCTTAGCCTGGCAT TCTAAGCCCTCCCTGACATGTGCGGTCTCATTCCAGGAATATTTTCCACTCCCCCCAGAC TCCACCTGGTGCATGTGGGCCATGCCCCCTTCCCCAGGCAGGCTCTGCATTCTGCTGCTC TGAGCCTCAGCAAATTCCCTTCTCTCTGCTGTGTACCACTCTCTGCTTCTCATCTCCCCT CATTCAGTCCTCCCCTGCCGCAAGTCCCAGCTCCTCCATGATGCCCGCAATCAGAAGGCC TTGCCCCCTCTTCTAATTCCTAGACTGCCTTATGGGTACCTCTCCCAGGACATGGCCACT TCCTTCCCAGCTGTAGCCCCAGGTGTATATGTGACCCTTCCCTATAATGGTCAGTGCTTG TGAGAATATGGGACACCCCTTTTTCATCCTCTCATCCAGCATGCGGCTCAGTGCCAGGAT TCTAATGGATAAATGTTTCCAGAGACTTCTAAGGGGGAAGCTAAATGTCTTGTTCTTTCC TAGTAGCTCTCCTTCTTGCATTTATTTTTAGCTGGATGTTTTTATGCCTCCAATTCTAGT TTGCCCATTAAACCAGCTCAATGGGTTAGGGAGGACATTGATCGTCATCCCTATTGTACA TCAAGAGAAACTGAGGCCTAGAGGGTTTAGGTGACTTATTTAAGGTCACTCACTTAGAAA GCGGCAAACTCCACCTGGAATCTGGGTCCAGCCTTTTGCCTCTGATGCATCCTGATTTAT TCTCCATGTCCAGCAGGGCATCCGTCCTCGCCACCTGTGGTGGACACCGTGCATGGCAAA GTGCTGGGGAAGTTCGTCAGCTTAGAAGGATTTGCACAGCCTGTGGCCATTTTCCTGGGA ATCCCTTTTGCCAAGCCGCCTCTTGGACCCCTGAGGTTTACTCCACCGCAGCCTGCAGAA CCATGGAGCTTTGTGAAGAATGCCACCTCGTACCCTCCTATGTAAGCTGCGGCATGTGTC CTTGGGGATGTTTACCTCAAAGTGATGCAGGAAGGAGTCAAGGCAGTCCCCTGATGGGCT GATCCTTTGCTCTGGACTCCTTAAGATCTTTGTAGATCCTTAAGAACATTCCAGAACTCT CACAGCATTCTGGAGTCCATTATTTAACACATGTTTATTGAGCACCTGCTGTGTGCCAGG CGTGTTCTGGGTTCTTGGGATCCATTAGTGAAAAAGCAAAGATCCCTAGGTTCCTGGAGC GTGCATTCTAGCAGGGGGAGACAGATAAGAACAATATGCAAATTACTCCGTGGATTATGT GATATGATAGAACAGGAAAAGTGCCTTGGAAACAAAGAAGCAGTTAAGCAGGTGAGGGAG ATCAGAAGGAAGGATCCCATGAATTCTGCTGTCTTGAATTTTGACATAGTCGGGGAGAGG AGTGGGCCAGGAGGTGTGTGGGTGGCAAGTGTACTGAGGTGTCCACTCGGCAAGTGCTCA ACTCTCAGGTGTGCCTATTCCTGAGGAGAACAATGGAAGGTGTGTCCATTCACCCTGGCC AAGCTGGGAAGAAAAGCCCAAAGGTTCTAATTGGCCTCACCATCACTCCCCAGGGTAGGA AGGACCCTACAGACATCAGAGCAGACCCTGCTCATCTCAGCAGCCAGGTGTTCGGAGGCT TTCCAGCAGCCCACCAGTGGCCGCCTTCTTTTCTTCCCTTTTTTAAAAAATAATGTTTAC TGTTTTTATTTTCTGAGTGCAAATGTAATATATACTTATTACAGAAAATTTAGGAAATAC AGAGAAAGGAAAGTAAGAAAATTAAGATCACATACAATATTCCACCACCCAGAGAGAACA ACTATCAGTATTTTAGATGGTAAAGTATTATGATGTAATATATTGTTTGTATTCCAGTTT TTTTGCCTGTTGATATACTTTCTTTCTTTAAAAGGGAATGCTATATTGAGATAATTTGGA TGCCTGCTTTGCTCATTTATAAGTATATCATGAGCATAATTCCATGCCATTAAATAGCAC AGCCTGGTATTAAAAGCTGCATTACATTGGGTATTGAACCATAATTAATTTCCCCAAGCT TTTATTTGGGGTCATTAAGTTATATATGATGTTTTTAATAATATAACATCATGAATGTGA AACATTTATGCACATTCATGAATAGTTTAGGATAACTTCTCAGAAATGACATTTCTGAGT CAAAGAGTATATATTTCTTGTTTGATTTCCCTCCCAAAATATTCCAACTACACTCCTCCC ATTGACGTATGAACATCTCCATTTGGCAGACTCTTGGCAATGCTTGGGATTATTAAAAAT ATTTTTGGCTATTGTATAGGCAAAATAATAATAACAATACCAGCAATATTATTTTCCTCT TTAATTTGCATTTATCTGAAGACCAGTGAGTTCTTTTTTCCTTTCTTCACATTGGAATGT ATTATTATTATTATTATTATTATTATTATTATTGTTATTCCTCTTGCACTTGGTGATCTT AGGAAAATTTCCCAGGATGGAATCAAGAAGTCATCTTTGCTGGCTCTGATTCTGTCACTT GAGAGCTGTGTCATCCCAGAGTCTGAGTGCCTCAGTTTCCTCATGTACCTAGTGGGGGCG GTGATGACTGCCTTTTGGTACATTGAGGTCTGGGACTGTTGCTTATAATATACTTGTGTA TAAGCACCACATGGCATGGATCTACCTGGCTATGTAACCTTGGTCAGGTTCTCTAACCTG CCTAGGCTTCAGTTTTCTCATCTGTAAAATGGAGATAATAGAACCTACCTAATGGGACTA GTCTGAGGCTTAAATGAGTTAATATACAAAAGGTACTTAAAACAGTGCCTGGAACACTGG GAGAACTAAATAACTATTACCAGTGTTCATCTATGTTGCATCCTTGAGATCTTTCATCAG GGCAACACAACAGCAACTGCCTGGGAGAGGCAGGTGGTAGAATCTTGGCATGTCAGGGCT GCAAGACTCATGTAGAAATCACTCCGCTCACTTAGACCTGGCGGATTGGGACGCAGAGTG TAAAAGGAATTCACCCAAGGTCACCCCATAAATGCATGGGAGAGACAAAACTAGAGCACA ATTCTCCTGATGTTGTCCCACAAAGATATCACCCCTGAGCTATTGTGAGAAATGTCACCT CCCAGGGAGGATCAGTGTATTAGTGGTCTCCCCTCCTTGATGCTGGGAGTTCCAAAGGCT CTGGAAAGGGAAGAGGTGTGAAGCCCTTCTCACTCTGCTTGGTCTTAGGAGACCTTAGTG AGTCCCAGCGCCCCCACCTGAAGCCCCTGATAGCCTCCTACCCACTACAATGTCGTGAGT CTGTAACTATCAAGTCCATTTCCAGGCTTAAACCTCCCAGTCCAAGGCGCTGCCGTAGAA AACACCTCGCTTAGATCTGGCTGAACTTCAGGGGTTCTTCTTTCCCCCTCCCCAGGTGCA CCCAAGATCCCAAGGCGGGGCAGTTACTCTCAGAGCTATTTACAAACCGAAAGGAGAACA TTCCTCTCAAGCTTTCTGAAGACTGTCTTTACCTCAATATTTACACTCCTGCTGACTTGA CCAAGAAAAACAGGCTGCCGGTAAGTTGTGGGACCCCCTGGTCAAGGCGTGTCAGTGCCA GTACCCCGCATCTTCTGGGGCAGAATGGAAGGGAGTGAAGGCAGCTTGGGGAGGGAGCTG CACAGGCCAGGATTGTTTCAGAGACCCCAGGGCCTCCACAGGAAACACTGGTTTTCCACA CATCAGTTTACCCTCGTGACATAGGCACTCTGGGGGAGTTTGTTTTGCATCTTTAATGAA CATCTTAATTGTTCCAAGTTCCCTCATGCTAATAGAAGGATGAGAATGATTACTTTTAGT TACTAGATTAAAAATCTGATACCAAGATTGGGTAAGACATGATTTTCAATGTTAGTGGTG GAAAGAACTTAGAGAAAAGCCAACACCCCAACTCTTCCTTTTCAAATAGAGAAACTGAGG CCCAGACAGGGAAGGGGAGGTCACCCAGTAGGGTAGTTTTGGCTCAAGTCTTCTGATCTT CACATCAGTGCTTTTGACATGGAGTAGGGCATTGAGCTTGTATGTGGCCTTTCTCCAGCA CAGCAACATTCATCTGGGGTAACTTTCACTGTCCAGGTACGGATGTTGGGGGCGGAGCCT GGACAATCCCAGAAGCTCTTCCTTTTGCCTTTGGCCAAATAGCTGGGATTTCTTTTTGTA CCTAATTTCCCTCCCTAATTGTCTTGGCAAAGGCTGATGACCCAGTGAGTCAGAATTTCC CAAATAAATGAAGGGCAGGACATGGGGCAGCCCGCCAGCTGCAGGTTGGAGGGTGGGGAG GGTCTGCTGGCAAAGGAGGCACCCAGGGTGAAAAAACAAGGGGTGTTGTGTCTAGCCAGT CTCCCAGGGGCACCGTGGCATGGTGCCTAGGAGTGGGGGAGCAGGTCTGCGAACGTGGAA CTAGAAGTTGGTCCTACATGTGCTTTGTGAGACACAGGAAGTGAGAGAAAGGTTTACTCA TTCATTCATTCATTCATTCATTCATTCATTCATTCTTCTATTGTGTACTCAGTGCCCCAT ATACACAGTTAGACCTGGGGCTTCAGGGAAAGGAGGAACATGAATCCACTCCACACAGCC CCTGCCTTCAAGGATCTTGCCTTCTGGGCTGTAGAGACATATCCTCCCTTCAGCACTTTA TTGCAGGCCAGCCCTCAGGCTCAGTCTTCACACAAAGATGAATGCACACTCAATCCCTCC CCAGGAGGCAGGCAGGGATTAGAGTTGTGGGAGAAACAAGGGCTCTGGGAACCTGGAGTC AGGAGAACCTCCAGGAATGGCCACAGGCTCTAGAACTACACGGTCTGGGTTTAAATCCTG GTTCTGCTTTTGACTAGCTGAGAGACTTGGGAGTTTCTTAACTTCTCTAAGCCTCTGTTT CCTCAAAATGGGAATCATCACATATGATCAGTCAAGGGTGACCACTAAGCGTGATCTCAG TCCCTGGCTAAAAAGGCAGAGGCAGGCTCATACCCCTGCCCTAACAGTGGACTCACTGCA CTGTGGCCGGCGCCTGCAGTGTGCTGGGCAGCTCAACATGTGGACTCTGGAGGCAGACTG CCTGGGTTAAAGTCCTGCTGCTACCACTTTTGAGTTGTAGGACCTTGGGCAGGTTAAGTG CCTCCATTTTCCCACCTGGATAATGGGACATTATTAGTACCTACCCAATGTATAGTTTAT TTTACTGTGCTTAGAACAGCACTTGGGACATAGTTTATGTTACGAGTTCTTTTATATTTC ATGAATAATATTATTACAATATCATTATTTTAGCCACTCTCACTTCTTCCCCACTATGTG GACTTTTAAAATGCAAGAATCATGCATGAGGAATTGTATCCACTCTCATCCTCCAGTATT AGCAGAGTCCCTGGCACATGCTAAGTTCTCGACAGTGTTAGTCCATTGACTGAAGGCATC CTGAAGTGGGTGGGTTTTAGGCTGGGTTCTGCAGGGTGGATAGGATTTGGGGATGCAGAG GCATAAGGAGGCATTTGAGGAAGAGACACCATCACAGGCACGTGTGCTTCTCGAGACAAT CATTCATGCACAGAGAAGTTTACTTCACCAAGAGATAGTTAACTGAGATGAAGCTGAGAT ACAAGGGCTGCCCCATGGGTACGCTGAGTGCATGAATAGTCTAGGCTTGAGGGTGATGGG AGTGTCCTCCCGAAGAGGACATCCTTAGCCTTTGCTATGCCCATGATGATGTTCTCAGCA TCAAGAGCCTTTCGGGGAGGAGGCACTGGAGGCTGGGTAGAAAGGAAGGGACAGCCAGGG TATGTGCAGTAGGGTGGTGGCTTGGGTCCCAGTTGGGAGAATTATGCAGGAGAGAGATTG CCTTTTGCAAAGTTGCTGGGAGCTGGTGAACTTTGGATAGCATCCTCCTTCAGTTGTAAC CAACAGGTAGGTCACCAAACAAGACATCTTCTGAGTGCTCCCTGGCTCTGTGTCCTGTAA CTGGTATGTTGCTTCCTCTCTGCCCAGGTGATGGTGTGGATCCACGGAGGGGGGCTGATG GTGGGTGCGGCATCAACCTATGATGGGCTGGCCCTTGCTGCCCATGAAAACGTGGTGGTG GTGACCATTCAATATCGCCTGGGCATCTGGGGATTCTTCAGGTAAGAAATCGGACTCTCC TCACTGCACTTTGGCCCCCAGAACGAGGATGCTAGGACCCAGCTCTGGTCATGCCAGCCC TCAGGGGAGCTTAGCTAGGTTCCACAGTAAGGCATCCAAGCCCCTTCGTAATTGGACACT ACCTACCCTCTCACTACCCAGCCACTCATCCACTTGCCTCTGAGCTTTTGCATGTGCTGT TCCCTCTGCCTGGAATGCTTATTCTATCCGAAGAACACCTCTTCATCCTGCAAGACCCAG CCCCCAGTTACCTCCACTGAAAGACTCATCTCCTCTTCACCTATGTTTCTCCAGCACATT GCTTTTCTCTGTCATGACACTTAGCAGTCAGCCCAGCAGGTGAAGGTTGACACATCTGAC TTCTCATGGAAAGGAGGGAAGGGGCAGAGTCACAGAGGGAGCTCAGGGCATGTTGTGGGT GAAGGAATGGGGGCTGCAGATGGTGGGGTGTGGGAGCATCTGACCCCTTCCTGTGGGAGT GTTGGGACCCACTCAGCTCATTTTCTGCTTGAAATTTGGCAAGTGTGGGAAGCAAGGATG GAGTCTTCCCATCAGGTCTCCATGGGGACAGGAGTCAGATCTCCTTCAAGGCGCAACTGC TATGAACCTTTTCTAAGGTTCTCCTCCATCCATGCCAGTCAGGTTTCTTCCTGAACACGC CACTCAGTTGGTCTCATTGCGGTCATCAATGACCTCCCCCTGCTCTCCACCCAACCTCTC AGGACCTCCCAGCAGCAGCAGATGGCCACTCAGCCTCTGTGACATGCTTCCTTCCCAGCC CCTTTCCTGGTCCTCCCTCCTCCCTGTCCACAGGCCTCTCTTGTCTCCCTCTCCCTCCTT ACTAATTCCCAGTGATCCCAGGGAGCAGCCAGAGCCCCTGTTTCCAGCCCACCTCACCTT TGAAGCCCACAGGCATCACTCACTCCCTCCTCCCCACCCCTGGCTGTCTAAAGGGTGCCC CACTCTTCCCAGGGACAAGTTGAATCCTTGACTCCCACTGCCCCTCCCCAACAGAGACCC CCTTCTCCTCCCACCACGCCTCCACTCAGCTTCTGCTGCCACATCCTCCCTTGGGCTCAG GAGAAGGCCTTGTGGACAGCCCGGACTGTCTCTTTTCTCACAACCCTCTTGGCTGCGCCT TCAGAATCCACTCAGAGTCCCCTACTTTGCACCTCTTCCCTGGCTCCTAGCCCAGCCAAA GCTCTCTGTCTGTCACCTTGATTATGATCTTTAACACTTTCAGATCCCTGCCACTTTTAT ATAAAGCTGAGTTGCACAGTAGCCAGAGTGATCACTTAACACATGCATTGAATCATGCGA TGCCTCTGCACAAAACCCTGCAGGGGCTTCCCATGCTCCTTACCATGACAGCCGAAGTTC TTGCCAGGCCCCAGGGCCCTCTCTAGCTGCACCTCCTGACTCACACTTTCTTTCACTGGG CCCCAGGCCCTTTGCACTTGCTTTTTCTTCTGCCTGGAATTCCTTTCTTTGGATATTTAC AAGGTTCATGTGCTCATTGTGCTTGTTTTATGAAGGTCTTTGCCTCCAAAACCTCAAATG TCACTGCCTCCAAAAAGCCTTCCCTGATTGGGATCTGAAATGGCACCCCCTGTCCCACTC CTGTTTTTTTCCTTACTCCATTGTATTTACCTCAGTGCACTTTGACTACCTGACATCATT ATATTCTCTCTATGTATCTGTTTATCTGCTTGTGATCTGTAGTGGGAATTCAGTGTCATC ACAGGTTTTGCCTGTTTTGCTCTCAGATGTGCTCTAGCTCATAAGACAGCGTCAGGCATA CAGTAGATGCTCAGTAAATAGTTGCCAGTTGTGTGAATGTAGAACCATACATCACCACAA TGCTGTACTAATGAAAGCAGGGTCTCAGAGATGCTGAAGCCCAGCCTTATTCTTAAGGGT TCACTGAGAACCCCTAGCCCCATCTGTGGTCCTGAAGGTCCTGCATGACATCTCTGCTCC CCACCCTCAACCTGTTCTCTTCCTCACAGCACAGGGGATGAACACAGCCGGGGGAACTGG GGTCACCTGGACCAGGTGGCTGCCCTGCGCTGGGTCCAGGACAACATTGCCAGCTTTGGA GGGAACCCAGGCTCTGTGACCATCTTTGGAGAGTCAGCGGGAGGAGAAAGTGTCTCTGTT CTTGTGAGTTTTCCTGTCACCAGGCCCAACCCCACGCTTGATGTGATGCTGATGAGACCT CTTGGACACCTGTCAATCCAGCTATGGATACCTCTGATTACAATACCTGAATTCAGGACT GGCCCTACTCACAGCCCAGCATCAGGGGGTAGAAAGCTAAAGACCAGCTCTCCTTGGCCC CCAGGAAGCTCAGAGCTCAGCTTAGTGTCCTGGGGCCATATGAATCTCCAGTTGCAGCCT GCAATGGTGGCATTCTCCTCTTCCAGCTTGGTTGAGCTCTCTCTCTCTCTCTCTCTTTCT CTCTCTCCTTCACACTCATTTTAACATAAGGACTCACATCCCTTCTCTTGGGAAGTAGGA ATAGGCATAAATTATGAGTAAGGGCAGGCAGAGAGAAGAGGTGGACAGAGGTCATTGTTT GGCTAAACCAGACCTACATGTGGAGGGGACATGGACACTGAGCAGGCTGGGAATTCCTCT GGGGTGGTCTGATGGCTTGTCCATGCCCAAGAAGGAGGCGACAGTCTTTGTGACTGTGGG GTCCAGTGGGCTAGGGGAGGCAGGCAGAGGAAGGAGGGATGGAGCCGCGGATAGGGAGGG ATGGGGCAGGGGTTGTGGGTCATAGACACAACCTTGGGTGTGAGGGGTCCTGCTGGGATT GGGGATTGGGTTCAGGAGACACTGGGGGATCTGGGATGAAAACCCAGATGAGAGGTGCTG GGAGCTGTAGGAAGACTTCCACCTCCTTGAGGTGGGCAGAGGGTCAGCCCACTACTGGAT TCCTCAGTCCCGTGTTGGTTTTATAGTGGAGTAGATCTAGCCTGGAATAGCGAGTGAGTC ACTGACCCCACTCCTGAGCATGAACTCTCCTCCCCTCCACTCTGCTGTCAGGTTTTGTCT CCATTGGCCAAGAACCTCTTCCACCGGGCCATTTCTGAGAGTGGCGTGGCCCTCACTTCT GTTCTGGTGAAGAAAGGTGATGTCAAGCCCTTGGCTGAGGTAGGTCTCCGGCTGGTACGT CTCCGGCTGGACACCCCCACCTCCTTGGCTCTATGCTCCTGAATCCTCAGGGATCTCTCT TGTGGTCGGTTGTAGCTAATGTTCTCCTAGAATCACTGAGGCACCAATGGCTGAGCAGGA AGGGCGAGGAGACACCTTGATCAGCGTCCCAGTTTCACAGCCAGGCAAACCGACACAGGG CTTGGAAGGGATTTGCCAAGGGCAGCAGGTGATCAGGGCAGAGCTGGGACTCCAGCTCAT GGCCCTAGCAGCCAGTACAGTGCCCTATCTGTGACCACACTCCTCCTATGTGCCAGGGCC TGGTGCCATGTTGGGCAGTGATGGTGTCTTGTGTCTCTCTGGGTCTGCCTAATGGCTGGT AAGTGGAACAACCAGGATTTGAAAGCAGACAAGGAAATTCAGGATTCCATGCTCTCTATC CCAGCTCCACCTCACATTTCTTGACACATTCACCTTGAGATGATTATGTCCATTTCAATG GAGATAAGGTAGCAGAGATGAGAGATTACATAATTGACCCATGTTACAATTGAGATTAGT AACAGAGGCAACGCTCCGTGGGACCTGGAACCCACACCCACGGGTCTACAGTATCTTCTG CTGCTCCCTGCCACTAGTACAAGTTGGGCTTGGGATAGAATGCCACTTTCCTCTTTGATG GAGGGAAGGGATGTCGCTCTTGAACTCTGTTGTTGCCTGTGATCTTTGCAGCAAATTGCT ATCACTGCTGGGTGCAAAACCACCACCTCTGCTGTCATGGTTCACTGCCTGCGACAGAAG ACGGAAGAGGAGCTCTTGGAGACGACATTGAAAATGGTAGGTTGCCTGTTCCCGTAGCCC AAACCCTGTAAACTTGGTCCCAGACTTCTTCATTTCAGCTGTCCTCTTGCCCAGGGACAG TTTCCTGGGACAATTTCTCAACTCTCAGTATCTGAATGGGGAATCTGATTTGTCCTTTTT TATTGTAAAATGCCACAAATGTAAAAAAAGAAAGTCAAAAAATAACATGATAAAAAATTG TGTAACAATCCCCAGTCCTGACCAAAATTTAATATTTTGCCATTCTTGTTTTCAGATGTA TTTTTAAGAAATTAAATGTTACATATTCCCAGGGGACACCATCATCCTGAATTTGGGGGA TGGAGATATTAAGCTCAAAGATTTTCAGAAAGATGTCACAATTTATCTTGGTTGACTTAG AAACTGTCTGTATTAGACCTAGTGGTGGTCCAGTTTTCTAGATTTTCTGAGACTGACTCA GTTGTCATCCTAGGATAGTCATCCATCCACCCATTCGTTAATCCGTCTATCTATGATTGT CTTATCCATCTATCTGTTCACTAATTCATCCAATTCACTCATATCTTTTTATCAATCTAA TGTCAACCTATTCATAACTTTGTATTTATCTATTTTCAATCCATTCACCATTCATGGATC ATCCAGCCACCTTATATCTCAACTCCATCACCCATTCCTCCAAAATCAACAATCCAATTA TCGCCTGTCTGCTAGTTTTCACCCATCTATTCATGTATCCATTCAATTCAACTGTACTCC ATGTATTGACCAACTCCATCCATCCCTCCATTGATCCATCCATCCATCCATGCTAAATAT GTAGGGGTGGGTGTTAGAGGTAGCAAAACAGACATGAAGTGGACATAGTCCCTGCTCTCA AGGAACTATCCAAAGAGAAATACATTCATATACTTCGCAGGTTGAGTATGGTGGCAGCAC AGAGGGGAAGCATTCATTGTAGTAATCAGGGATGCTTCACAGAGAAGGCGGAGGAGCCAG ATTTGAGACCAGACAGTGGAATTCAGGAGTTCATGCCCTTAATCCTGACTCCACCTTATC TTTCCTGAGAAATTCAGCTTTCAGATCATTGTGCCCATTTTAACAGAGGTAACAAAGACA GATAAATTTTGTAATTGCCCCATGTCACAGTTCAAATTAGTCACAGAGGCAACACTGTAG GACCCAGAACCGACACCTGCGGGTCTAGAGTATCTTCTGCCTTCCCTGCTCCCTGCCATC CTCACATATTAGGACTTGGGGACCTTTAGGATTGTTGGATGGCCATGGCAGTCTCTCATC ACAGGGAAGACCAGGAGGACAAACACCCAGATGACACAGCACCCAGGGCCATTGGGAACT ATTCCCTTTGAGGGGGAAGAGTGTGAATTCCAAGCTCAGGAGTAGCCTGGACTCTCTCCT TGGACCTGAGGCTACTCCTGGATCCCAGGGCTGGCCTCTACCACTGGACTCTGCTTGTGT TTCCATGAGTTGAGTCCAATGTGGTATTGGTGCTTAGGTCTTGGCTCAGGCTCTAAGTGA CCAAAGTGTTCAAGGAATGAAAACACAACTGTTTTCTAACGCCCGGAAGGAGGCAAATAT TCCAGCAATTCTGCATGTGGCATCAGAGGACCCAGCTTAAAAGGGAAGAGTTGAGTCTTT GGGAAAACCCATCCCTAAGATCCTAGAACATTCTTTTGAGTTTTTCTGAGATCTTGTGGA AGCACCTCCATGATTACGCGCTGCCTCCAGTACACACACATGCAGACACACAGACAAACA CACACACACACAGACACACACACAGAGAAACACATACAGACACACACACACAGAGACACA CACAGACACCCACACACAAAGAGCCACACACAGACACACTCATACACACACACACACACA CTCCTGGCTAGTGGGACTTCAATCCTTAATGGAGGGACCTGCACTGGTTACATCCTGAGC ACAGGTCAGATCTGGGAACTACAGTGCAACACTACAGTCACTGCAATCTTGGTGAACACA CACCAAAGAGAAGCATGGGGTAGGATGAGACTCAGTGAGCTTGCGTGAGTCAGGGCTTTC TAATGGGAGATGAGGAAACTCTCCCAAGTACCTTGAACAGAAAAAGAAATGTGTTGCAAT AGCATCGTCGTGTAAACTGAAAATCTCAGGAGTTGATGGCTTCAGGCATGGCTGGGTCCA GATGATCATAGGATATTATTGAGAATCTACCATTCTCTGTCCTTCAGCTTTGCACATCTC TGTGTTGGCTTCACTCTTAGGCAGATATATCTCCTGGGAAGGTTAAAGACAACAGCACTC TAGACTTATGTCCTATCTGCTTAAAAACCCTCTTTCTAAACAATTCCTGCAAAAGTTTTG GGGTAAACTCTATTGGATTGACATGAGTGTATGCCCATCCCTGAACTAATATTCATGTTC AGGGAGATGGAGCACCGCAGGTCACATATAGATATACGAATTCACGGAGTGATGCGGGAA GAACCTGACACCTCTGTTGCCCCACTCACCCAGCTCAGTGTTCTCCTGGTAAGCCTCTCA CCCACATCCTCTGCCTTTGTCTTCACAGAAATTCTTATCTCTGGACTTACAGGGAGACCC CAGAGAGGTAAGGACCTTTTGTTTCTGGATTACGGGTTTTGAGTCTTAGCACCTTTAAGC TCCAATTAACTGTGAGTGAAAGAATCATCTCTTGGGTAATTATAGTAACTCCTGCGTGTT TGTTTCTGAGGCCCAGAGAGGGGTAGTGACTCACCTGGGTAACACAGCCAGGAAGACTAG TGGCTGGCCTGGAACCCATTTTCCTGACTCCCAGTCCAGTGCTCCCAGGCATCACCTCTG TGTGCCCTGGGCTCTGCCCACTCCCCTTCTTTTTTACATTTTCTGCTCCCCAAAATGGCA CTGTAGGAGGAGGCTGAAACAGAACCTTCCACAATCAGGAGGCAGAGATAACAGCGATGA TTAGCCAAGGAGAGGGGAAGCCTAAATCTCAGTCCAAGGACACTCGTCTCCTCCCAGCAC ACAGGAAACTCCAACAGTATTCTCCCAATCTCCTCATCCCCACTCCCACCCCCACCTCCC AGTGGGTTGACAGTTTCTGGTGACATCACCTCTGACGAATCTTACAATCCTGTCCTCTCT GCTGCCTCCCTGGAGATCACAGCACTCTCCTAAATGGTCATGGGCGGAGTACATGAGATT CATTCAGCAAAGACTTAATAAACACTTCCTATGTGCCAGGACTTGTTTAGGAGCTGGGGA TATAACAGTGAAAAAAGAAAGACTCCCTACCCTCTTGGGACCTTCCATTACAGTGCCAGG ACAGTGCAATAAAAAAGCAAATCAAGTATGTATTCCGTTTGATGGTGTGCAGCATTAGGG GATAGAGTTTGTGGGTGGCTTCAATTTAAGTAGCAGGATCAGGGAATGGTTCAATGAGAA GGTGGCATTTGAGCCAAGCTCTGGAGGAGGCAGGAAGCCAGCTGTCAGGAAACCTGGAGA AGCCTATTCCAGGCAGAGGGAACAGTCACTGCAAAGACCCTGACAGAAGGGGCCAGTCTG GCTGGAGAGGACCGAGTGTGGGGACAGACTGGCTTGAGGCTAAAGAGGTAATGGGCAGTG GGAGAGAGATCAATTAAAGTACTTGGATTTGGATTCAGAGCAAGATGGGAAGCCTTTGGA GGTTTTGAACAGAGGAGTCACATGATCTTAGATCTCACAAAGGTCTCTGTCTCTGGTGTT CAAATAGACTGTAGGAAAGGGGCAAAGTGGATGCAGTTGACCAGCTGGGCAGCCACTGCA TTGCCATAATCCAGGCAAGGGCTCCTGGCTGCTTAGACAGGGCTGTGGCAGTGGGGATGG GAGGAGTAGTTGGAGTCTGGATATCTTTGAAGGAATAGCTGACAGGATTTGCTGATGGAC AGGATGCAAGGGGTAAGAAACGGGGAGGAGTGGAGGACGCCCTGAGTTTTCTGACACAAC AAGGTTGTGCCCACACAGGGCAGCCACTTGCAAACTCTAAGTGGAGAACAATCACTTGTC ATTGTTGCTGATGGCAGTCTTCCAGCATGGCTGTCACCCAACTGAGGTGCTCCCGTCTCT TGCCTCAACTTTTAGCCTCTTCTACTTCACCTTCTCTCCCCATTTCCATGTCTCATGGTG CAGCCAGACTGGCCTTCCTTAACAGAATTAGAGCACGTCACCCCCACTTCTTAAAAGCCT GACCTTCCTTATGAGACAAATCCCCTTCCCTCCATGGAGTTAGTCCTTCAAAACACACCT GCGTGCACACTGTGTGCCAGACTGTGCAGAAGGTAGGCTCTGCACCTGTCCCTCCCTCTA GACCCTGCCCCACAGCATTTCTCCAAGCCAAGAACTCTTGGTTGTTTCTGGAATTTACCC TGCACAGTGACACCTATGTCCTTTTGCTCATGCGGTTCCCACTGTTTAGAAATTCTCACT CCTTTCCTCACCTGGCAATACCATTCACTGCCCAGAGCCCACCGCAGGCAGGCGGCGTCT CTTCCACGTAGTCTGCCCTGCATCTTCCTTCCAGAGGGGCTGCTCCTCTTGCTGGCCTCC CACAGCAGCCCTGCCTGAACTGCACAGCCTCTTAAGGAGGCTGGACTTGCACCCCAATCC TGTTCTTCATTGTCAGCCATATTGGATTAGGATCTGATCTTGTCCAGCTAGGTCTGGTCC ACTTTTCAGAACATCTCCCCCAGGCAGTCCGAACTAGCTCGTCATTCATTGGCTTTTGTA GAGCAGACCAAAGGTCCCAGAAGCCATAGGGTCTCAAAGGCTAGGAATTGTCCAGTTCCA TCTGATATCCAGAAGGGAAATACAGCCCATGGGGCGTGGAACTGGGAAGATTCCACAGAG GACTGGTGTCTATGAGAGGGACCCACAGCAACCTTGCTAACAAGTAATACCTAACAGTTA TTCAGCCTTTCCAGACACCAGGTGCTGTGCTAAGTATTTTACATGTGTTCAGCCATTTAA TCCTCACAATAACTCACCTCTTAGATGAGAAAACTGAGGCCCAAACAGGTGAAACTCCCA GCCAGTAAGTAGCAGAGCCAGGCTTCAGATGCAGTTAATCTGGTTTCAAAGTCCATGCTC TATCTTAGCAACATCCACGCTCTATCGTAGCAACTACACCATTGTGACTAAATATGAAAT ATAACTGTACCCAGAACCAGCTGCCCTGATGGCAACACATGAGTTGGGCTCTCTCTAATC TGTGACCATATAAAAATTATTCATCAAAGGTGAAACCTAAAATTAAGACATGGATCAATA TACTGTGAGTTAATCACTGATTCTTTTACTCATGATTTTCTCTCTAGTAGGGAATCATGT CCTAGTCTAGGCTCCTTGAGTGACCAGGGTTCGGTACCTCCTCAAAGCCACCCGTGGATC AATAACAGCTCTTGTTTAAATACAGATAGATAGCATAATCTCTTCCTCATTAATCATGGA TTCTGTGTTTATAAATTCACCTGCTTGCTAAAATGTCCTTATAACCCCCAAATCAATACT GGTGGCACTTTCATGGTCACACACAGGCAGGTACAGAGCAGGGGAAGCTGGATTTGCATG ATGGGCATGTTCCATCTGAGATCCGGCGAGGCAACCTCTCTCTTCTTGTTTCATCTCTGA TGTTTACAAGTGTCCTCTTCGCGGTCTATTTAGTGCCGTGTGTTCTGCATTTTTGTGCTT TTTGTAGTGATGTCACTGTTTAGAGCGAACCCAAGAGTAGCGCTGCTGTCTGGCGTTCCT GAGCTAAACAGGCTGTGCTGTGCCTTACGGGGAAGGTGCCTGTGTGAGACAAGCTTGGAT GAGGCAGGAGCTGCAGTGCTGCTGGCCGTGCATTTGGTGTTGAAAAATCCACATAATAGC ACATTCAGAAAAAGGAGAAGGAAATTGGCCGATTCATACATGAGGCTGTGATAGAAAGGG CTAAAGTAACACCTATTGTGTGGGATGGAGCCGTGGAAGTCTCTTTCAACAGAAACCCAC ACATAAAAGAAGGTTGATGAAAATGTTGTGGCCAGAGGTTTGCAAAAACCTAACCCAGTA TTTCCCCCTTGAGTGATGACCCTGTATTCTCTAATTCAGTACTCACGGGGGCTTTATCAG AAGCAACTGCCAGGACTACCGAAAATCAATTGTGGACACACAGAGGAAAATGCATGCACT TCAAATTGAAATATATAGACATGTAATTTTACATAGATAATACATGTATTTCAATATGAG TGAAGATTTCTTCCTCTCCTCATCACCTGAGCAGTGTCAGCCTCTGCCTGAAGTTCTGCC CCTGAGTCATGGAGACCTACCCCCCTAAGTTAGGATCCTGAGCATGTGCAGCCATGGCGC ATGGCCATGCCGGTCTATGGTACTGGTCTCACCCTCAGACAGGCAGAGTTGGGGACATGG GTGTGACTAGGGAGGGAATCACAGGTGCTGCACTGCTCTCTCCCCAGAGTCAACCCCTTC TGGGCACTGTGATTGATGGGATGCTGCTGCTGAAAACACCTGAAGAGCTTCAAGCTGAAA GGAATTTCCACACTGTCCCCTACATGGTCGGAATTAACAAGCAGGAGTTTGGCTGGTTGA TTCCAATGGTGAGAAGGCACATGTCTGTTGGAGGGACTCAACCACCCCCATCAGCCCTCC TGTCTCTGGTCCCAGGAATGCTTCCCTCTCCGAGCTGCACTCTGAGTCCTGGGCAGCTGT TCCCTTCAGCAGGAGTTAACATTTCCACGGAAATCTTCTCCAGGAGGGCACAGTTTTCAC CGGGGTATCAGGGCCCTGGGATTCCCTCTCCCCAGACTCTCTTATTGTCTTCCTATTGAA GAATCCTGAAGTGTCTGTGCTGGGAGGGCCAGTAGAGAAAATAACTCTGCAGATGGGAAA ACGGAGGGGGCCTAGAAGGGGGAAGGAGTGGAGGAGTCCGGAGAAGCAGTCGGGGGCTTC CTGGCTTCCCACCTCGGGCTGGGTGTGCGTAATTCCCCTGAAAATCACTCATGCTCTTCA TCACCTCATTGAAAATATCCAAAGAAAGTGGCTTCTTCTTGAGTTACCATTGACTTCTAG GGAACAGCAGACATCAGCGTCTACTAAGAGAGTGGATGGTCAGAGGAAGATGAGGATGGA AAAGCTACCTAATCGGGTGCTATGCTCAATACCTGGTAACAAAATAATCTATACAGCAAA CTCCAGAGACCCAAATTACCCATGATCAAACCTGCACAGTTACCCCCAAACCTAAAATAA AAGTTGGAAACAAATAAATGGAAAAAGTAATTGAGTTCTAAAAGTAAAGAAGTGTTCTCC TTCCAGTTGAAGATAAACAAAACTGACCCTGGTTAAAGCAGTAGGACAGATTTATTCAGT AATATGATTGCAATAGGGGAAATAGTCCAGCGTGGAGTGGACTCACATCCCTGAAACAAA AGCCTGATGACGTTTCATAGGCCAGGTGTGCCAAGGGAAACACTGTGGTCTATGGGGAGA GGCTTGGTTCATGTGACTAGACCACCTGGATGTCTTCATCCTGGCTCACCTGGGGCAGAA ACAAACTCCTCTTATCTTTAGGACAGGAAGCCATGCATTAGACCGCAGGAAGAACCCACT GAAGTCAGGCTCTACTCTTTCGACAGGGACTGGGAAGATCAGGAGTGAGCTCCCTGAATG TTTGCATTGCAAAGAGAAGGCTCTCAGGTCCTCAAGGAAATGGGGTTGGGTGGTAGATTC ACATCCCAAAGGGCAGAGAAAGTGTTTATCATTGCAGGCTTCTAAAGTAACTGCTCTAGT TGGGTTCGGGGACCTGGCTGCTTGTCTCCAGGTTTTGGCTGGAGCAGAGTAAATTGTCCT GGCAGGGTTGAGCCTTCCCAGGCAGTTATGTTAAGGATACTGGGGTCATTCTAGGGACAC AGCCTTAAGCTGCTAGAAGCAATGCTAGAGATTGGTCGAGTCCCTGAGTGCAGAGGTTTG GGAAGAGTTGTTATGTGCGTAGAGATGTGCAGTTCGCCCCTCAGAAGGATTTCAGAGGTT ATACCAAAGACCAAAGCCACGAAGACAGGATTTAAGGATTTCAGTGTCATCTGTGACAGG TGGGGGTACTAGGGAGGTCTACATCCTCTTCCCCAGAGCCCTCTATTCCACACTGGCCTG GCAGACACCTTGCATCTCCATGTCACTGACCACTGTAGGGATCCCAGCCACAGACACACA CACACACACGCGCGCACACACACACACTGCAAAACACTGCCACAGCTTCTCTGAAATTTT GTTTTTTGTTTTTTTTTTTTGTAAACTTTGCAATGCTTGAGTTTCTGGATATAAGCCCAT TTGATTCATTGATTTCACCCATTTCAGTAAAGACTCATGCCCTTAAAAGCCCCCATAATT AGAGGACTTTCAGACTGCATTGGTTTGGTTGGTTGGTCAGTTTGTTTCTTATCATTAATT CCCAATGATTCATAAATGCTGAACTTTTTTTTTTTTTTTAGCAGTTGATGAGCTATCCAC TCTCCGAAGGGCAACTGGACCAGAAGACAGCCATGTCACTCCTGTGGAAGTCCTATCCCC TTGTTGTAAGAGTCTAGGAATCATGGGAATTGGCTGAGACCCAGAGAGGGACAAGGACTT GCCCAAATCATAGAGCAATTAAATGGCAGAATGAAGACTGGGGCCTCAGGGTTTCCCCCA TCTTTCCACCTTTCCCACTTCATTTTCCACCCTAGCGGGGAGTTGCACAGGGCTTATGGG GTTCACCATTGAGGCAGGACTTTCTGGTGGGCTGGAGAAGCTGCATCGCTCACCCGGGGC TGGTGGTCACTTTTTGATCTATTTCAGTGCATTGCTAAGGAACTGATTCCAGAAGCCACT GAGAAATACTTAGGAGGAACAGACGACACTGTCAAAAAGAAAGACCTGTTCCTGGACTTG ATAGCAGATGTGATGTTTGGTGTCCCATCTGTGATTGTGGCCCGGAACCACAGAGGTGAG TCCCAGAGGTCGAACGGGAGGGACACAAACCCCACGAGCTTCTGTATCTGACCCACCTAC CTCCCAGCATAGACAGACATGGAAACAGCTGAGGGTCAGGCCTCAAAGGCTGATTCCATA TGGCATGGGATGAGGTGCTGTCTTATTTTGGTTTATGCCAGCAGAAGACTGTGAGAAAAA AAAATCCAGAGGCAAGTGGTTTTTTTAAGGTGATGATCCCAGATAACAGCAGTAGGGAGG TGGGGAAGTGAGAGAGGAAAGAGATGGAATCCAATCCAAGATGCGTTGTCAAGGGAGTAT CCACTGTGGACAACTGGAGCGGGGAAACTCAAGGAAACACCAAGAATACAGGGCTCAGGG GCATCCCATCTGAGTGGCAAGGGAGCCGGGTATTTATTCACCAGCTTCTACTTGTCATTG GTTGAAGGCTCTTGCAAGGAATTGTTTATTCCCTGTGACTTCGACCTGCTGCACACAAGG GCAGAGTAGTCTCTTGTGACCAGACAAAGGCCTCAGGCCTGGAGCTGCAGATGCTGGAGG TGGAAGTCAGGCTGGCATGCCCAGGAAGAGGGGATATAGGTGAGACCCTGGCAGCATCTG CTGCAAGGGCTCCATGCCTGGAGTTATTGTGGGACATAGGGCTGCTGTAGGACAAATATT GAAAGATGAGTCGTGGAAGGGTTTTAAGGTCTGAGCCAGCTGCAAACAAGTTTGTTAAGT ATTGGAGCTGGATAAAAAGTGGGAGCCCTGCATGGGATCCAGAGGATTGTCCAGGACCAA GAAGGCCAGAGAGAGGAGCCAGGGCGGGTGTGGGAGAGGTGGTCTGTAGAATGGCAGTGT CTGAGGGTGGTTTTTATGCATCTCAGTGCGTGCAGTAGCATGCAAGCACAGGGCAAGGGC AGGGTCTATGCAGGACCTGCTACCACTGACCCAAGGCTGTGTGGGTGGGGCATGACGTTA GGGATGTGTGTGCTCACCTAGAGAGGAGTGTCTGTTCCTGCGTGCCAGCTAGAGGAGATT CACAGGATTCCTTTTCTTCCAGCTCTCATTCGCCTAGTCTGCAAGCTAGGAAATGTCCTC TCTCTAACCATGCTGGAAGGGTTTTTAAATTTAGAACTTCATAAGCATGATAAAAACTAG CTAACGCTTAACTAGCAGGTGCCCTGACACACCTTTGCACAGGAAGGGGCAGGTGCTCAT AACCCTCATTTCTTCACAGGGTCCTGATAAAAACCTTTAACCAAGACCACTGGAGTTGAA TCTGTTCTTTCTTAAACTTGCCCTTGCCCTATGCTCTGCGTCTGAACTATATATAGAGTT CCCATCTCCATTTTCTGATGGTTTGAGCAATACTGAACTTATGTTTTTCATCTGGTTTCC CATGACTTTAAGTTCAGGGCTTTTTTTTTTTTTTTTTTTTTTGCCAGGACTACACAGATT TTATCTACTTTCACTTATTGTTGTCTCACTCTTTTTGATAAAATAACATTTCTGAATATA AAATTAATATGTTAAATTATAGAAACTTTCAAAAATATGGAAACACAAAAAGAAGAAACT ATGTATCACTCATTTCCACTACCTGGAGGCAAGTGCTATAAATTTTTTGTGTTTTCGTCT AAAGATTTTCCATGTCCTATATACTTTAAAAATCAATTTTATATTTTACTTTTGTTCATA GAACACTATGTTGTGAGGATTTTCTCAATGTTGATACAAACTCATCAAAGCATTCCTTAT TCCATGAAATGGCTGTGTTAAATAGACTTTAATATTCATATCCTATTAGATGTTTAGCCT GGCTACTCACATTCTGATGCTACAATAACATTGAGCTCAGCCTAATGTTCATAAGTCTCT AAACACATGTCTAATAATTTTCTTAGGATTATTTTTAGAAGTAAATAACTAGGTTGGACA ATGCAAATGTTTTAGAACTTTGGGCAAATATTGTAAAATTGCATTCCACTGCATAAGAAT GTGGATTTCTTAATTCTCTTTCTCATTTGGGATGCTAAGATTAAAAATTAGCATAACACT TCCAGTTTCATAAGCCTTCCCCACCAACAAGAAGCACATCAGCCTGTTTTAATCTGCATG TCCTCCATGACTAGCCCTCTCATTGTCTCTGCTTCTCTTATTATGTCTAATTGTCATTAC CCAAATCTGTGCGCTACTTTCCTCTGAAGACTTGTGTTGTGATTGTAAGAATTGTATAAA TATCAATGGCTTTAGCCAAAGAGTTTTACAAAGTACGTTTTGGGCAGCATGCTGCCTATA ATAAGTTCTATCATTCACAAAAGCTCTTTCTTCTATGGTTGGCTCTGAGTTTCTTTGGAA AATGTTCGAGGGGCAAAGGCAAGGTCAAACCCTCCTTTTAGCAAGTTTTGTTTGACCTTG AAGCAGCCATTTAACAGGTGGATTACAGAGCCACAGAAGGATGGCATCTTCCCAGGTGCG CTTCCTGCTGAGCCGAGGGTGCAGTGCAGGAGGCTGACAAAGATGAGTGAATAGATTATT CTTCATTCTCACATTGAAATGACATGTGCGGGTGGGGCATGAGGTTAGGGATGCGTGAGC TCCCATTGTTAAATCCTTTTGTGAACGAATTTTTAATGATGTTAAGAAATGATGGCTGGA GGCGGTGGCTCTTGCCAACACTCTCAGCATTTTGGGAGGCTGAGGTGGGAGGATTATGAG AGCCTAGGATTTCAAGATCAGCCTGGGCAGCATAGTGAGACCCTGTCTCTACAAAACAAT TTAAAAGGGAAGTGATTACAGTGTACTACAAAATACCATATATAATATCATCCCCAGTTA AATACATAAAAGAGAGATATGCTAAAATAAAAAAGAAGCATTCTCTGAGTGGTAGAGTTA TGAGTGATACTTTAAATTTGATTGTTAAAATTGATTTTTAAATTATATAGGATATGGAAA AATTTTAGAAGGAAATACAAAAAATGCATGGCCCTTGCCTCAGGTAGTGGAATTATGAGT GATATCTAGTTTTGCTTTATGCGTTTCCATATTTTTGTTTCTTCTAATTATTCCTAATTG TTTTTATTTTCCAAATTTCTTACTGTACCCAAAGGGGAGGACATTGTAAATTTTCTCCAC CAGCCTGGCATTGCCCTGACTCTTTCCGTCTTAGTGTCACTTCTCAGTGGGTATCATGAC CAGTGCAAAGTGCTGAGGCACAGGGCCAGGCGGCCCACGAGGTAGCCCTGAAGGGGCAGC GATCTGTGGCTCCAATGAGCCAATCATTGGGAAACTGGCATCTTCCTGGGGCTGGGACAG GAGAGCTTTGTTGGTGGGAGAGGAGGGCAGAGCCGAAGGAGAGAGGGCAGGGGAGAGGCA AGGTCACCCTTGCTCAGCGCCTTCTTTTCTCTGCCAGGGCTTTACTGCCTTAACACCCTA ACACTCCCAGGCCAGGCAGGCAGCAAGACACATGGGGACAGTGAGCTATAAAGCAGTGAG TGCCGCAGGTTCCTGAGACACAAGAGGCAGATTGTTCCCTCTCTGCATATGTTTGTATTT AAATAGCCTCATGTTCAGACAAGCAACTTGGATTTGCTTCAGTCTTCTCAGGATGGGTGA GAAAAACACTGGAAATGCTCAAAACGAGGCAGAACAGAAGACACCTGTCATGGTGGAGAT GGCATCCAAGTGAATGAACGCGAGTCTGTTATCAATGAATTATATCCGGTGTAACCAGAT GTAGAGAGATTGTCTTGTGTGAGAATGCACCAGCAGGCAAAGGGGTTTACGAGGCAGAGT CAGGGTCCCTGCACCGGCAGCTGTTTTAAATGAATTGACCCAGGGTTTCCACATTCATTC ATTAAACATTTGTTCATTGAACAAATATTTGGCTCTAATTCCGCTTCCACCTCAGACAGC TATGCAGCCCGGAGCACATCACTGAGCTTTCCTGAGACTCTGTTTCTCTACTGTGCTGAC AGCCAGAGGTTTGCTGCAGAGCTGGAGACCTTGGTAGCCTCCAGGTGTGTGTCTGGCAAC ATGAACTGTGCATGAATCCTTGTCTTCTCAGATGCTGGAGCACCCACCTACATGTATGAG TTTCAGTACCGTCCAAGCTTCTCATCAGACATGAAACCCAAGACGGTGATAGGAGACCAC GGGGATGAGCTCTTCTCCGTCTTTGGGGCCCCATTTTTAAAAGGTAATGCTCCTTCCTGT CTGTGAGCTAGGAGTTAGAGACTTGGGTTCCAGTCTTGGTGTGGTGGCCTTCAGCAATTT TGTCCTCTCCTGGTCTTAGTTTCCTGATTCTGTATAACAGGGTTGAATGTCACTGGGTTG TCCGCCGGCTTCCTCCCACTCTAACACATGTGAGGAGGGATGTGTATTCATGTGCCCTCT GCACAGACGCTCAGAATCCTGCTGTGTGACATCAAGACAGGTGGTGGTGGGGGTCTCCTG CAGGATTCACTATGACAGGGTTGAATGTCACTGGGTTGTTCCCCGGCTTCCTCCCGCTCT AACACACCTGAGGGAGGATGTGTATCATGTACCCTCTGCCACAGACACTCAGAATCCTGG GCTGTGTCATCAACAAGATAGGCGGTGGGACACATGCGGGGCCCTGCTCTAGGTTGAGAA GCCACCAATCAATTTCCCTCTCCCAGGAGCGCTGAGACAGTGAGTGAGGGTGAGATTAGA ATTGGTGTTAACCCTAAGTCAGGTCTAATGTGTGCCTGTTTGTCTTTCTGTCTGTCTCTA ACAAAAACTCATAAACCTTTACATTTAGTACATTTAATAATTGTTGATTTAGAATTCACA GGATGTATGAATTTGGAACAGGAGAAGAGAATATTTTTTATATGGTTTATAGTCAGCAAG GTGGCCATCCCACAGGCTGGGAAGGTGCCTCTGGCCAAGCCCAGAAACGGGCTCATTGGA GGAGGGGTTGGGTAGGAGCTTTATGTGAACGGATTGGCTAAACATACATGTTCAACAGGT TACAGGGGGAGCAATGGATATTCATGAAGACAGTCCTGACACATGTGTATTAAACAAACA TGTATGTAACATGGCCCATGTTCACCTGGTGGTGGAGACCTAATATTTAAATGTATTACA ATTAGGGCCTGTAAGTCCAAAGGTCTTCTCAGGACACGAAGCTCAGCAAGTGAGGAGCTT CTGTACACCGGCCAGGTCCAGTCCATGGCTGGTGATGTTCTTATCTGGAGAAAGTTACTG AAATCAGTCTCTTATGCAATCAAAGCAGTAGTTAAGTCTGGCAAGTCAGGGTTCTGTTTG TCTGCGTATCCCAGCTGCAGCCGTTGTTATTGTTTTCCTTTTGCTTAGCTCCAGGCCAGT GCTGGTTTAGCTGCTAGAGAAAGAGAAGCACCTCGTGGCAGTGAGAACAAAGTGGATTCT TTTTTTTTTTTATTATTATACTTTAAGTTTTAGGGTACATGTGCACATTGTGCAGGTTAG TTACATATGTATACATGTGCCGTGCTGGTGCGCTGCACCCACTAACTCGTCATCTAGCAT TAGGTATATCTCCCAGTGCTATCCCTCCCCCCTCCCCCCACCCCACCACAGTCCCCAGAG TGTGATATTCCCCTTCCTGTGTCCATGTGATCTCATTGTTCAATTCCCACCTATGAGTGA GAATATGCGGTGTTTGGTTTTTTGTTCTTGCGATAGTTTACTGAGAATGATGGTTTCCAA TTTCATCCATGTCCCTACAAAGGACATGAACTCATCATTTTTTATGGCTGCATAGTATTC CACGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTG GTTCCAAGTCTTTGCTATTGTGAATAATGCCGCAATAAACATACGTGTGCATGTGTCTTT ATAGCAGCATGATTTATAGTCATTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAA TGGTATTTCTAGTTCTAGATCCCTGAGGAATCGCCACACTGACTTCCACAATGGTTGAAC TAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATCCTCTCCAGCA CCTGTTGTTTCCTGACTTTTTAGAGATGCAGGCCTGAACCCTTGCCCGACGTGGCCTTAG GTCTCGTTTTTAATTTGGTGTCTTATTGCCACAAAGAGTGTGTTCTGTCAGAATGATGAC CTTCATTTTATTGCTGATGCTGGTCCGGTGGTGTCTAAATCACAAAAGGGAGGGAGTATT ATGAGGCGTGTCTGACCTCCTGTCCGTTCCCAGGCAGGAACAGAGTTGAAGGTTTTTCGA GGCTCCCCTTAGCCCAGAGAGGGTCTGTTCAGTCAGTTGGGGGTGTCAGGATTTTATTTT TAGTTTACATTATACAATAGTTTAAAAAATCCTTTCACGGTGTCTTCTAAGTCTTAACTC TCAGCAGTTACAGATCAGATGGGACTCACCCCATGGCTGCTCAGAACGCACCAGCGCCTC TGGGCATCTCACTGTGCATGCTTAGGCGCCTTGCGGCTCTGTTGTTTTTCAGAATGTGAA TTGTGGGTGTGTGCTGGGGAGGGAGAAAAGACCCAAGAGAGAGCAACCCTGGAAAGTGGG GTTGCTGTAGAGGAAACCCTGGGGTGGGGCATTTCCTGTGACCCTGAGCGGGGAGGAGGC AGGCGAGGGTCACAGGAGACAAAGGCAGCCAGCCAATGGAATGACGCATGCCCATTGCTG AGCCCTAGGTCAGATATGCTGAAAGGTAAAGTACACACAAATCCACCACGATCTTCTAAA AGTGCAGACCTCAGCTCAGTGGGTGTGGGGCATGTGCCAAGACTATGTTTCCAGCAGACT CGCATGTGATGTTGACGCTGCAGTCCACGGACCACACTTTGAGTAACAAAGGCTTTTTTT CTTCTTCCCCACAGAGGGTGCCTCAGAAGAGGAGATCAGACTTAGCAAGATGGTGATGAA ATTCTGGGCCAACTTTGCTCGCAATGGGTGAGGCTGGTGGCAAAGACAGAGCACGGCTGG TGAGGGTGGGGGGCGGGGCATGCCTATTGGGAAGGGGCAGCTTCTAAGGTTCTAGTGATC AAACTTCTGACCCTGTGACCATAGCACTCTGATAATGAGAGCTCTCTGCAAACGGAGAGG CCGCCCCTGGAGATAGTGAGCTCTCCATCTCTGGAGGTATACAAGCCTCTTGACAGAGAT AACTTGGGCATCCTCACACATCTCTGAAGATTGTTGGGAACACACAGCAGCTTTGGGGCA ATTCTAATTGATTCTGTTTCCAGAAACCCCAATGGGGAAGGGCTGCCCCACTGGCCAGAG TACAACCAGAAGGAAGGGTATCTGCAGATTGGTGCCAACACCCAGGCGGCCCAGAAGCTG AAGGACAAAGAAGTAGCTTTCTGGACCAACCTCTTTGCCAAGAAGGCAGTGGAGAAGCCA CCCCAGACAGAACACATAGAGCTGTGAATGAAGATCCAGCCGGCCTTGGGAGCCTGGAGG AGCAAAGACTGGGGTCTTTTGCGAAAGGGATTGCAGGTTCAGAAGGCATCTTACCATGGC TGGGGAATTGTCTGGTGGTGGGGGGCAGGGGACAGAGGCCATGAAGGAGCAAGTTTTGTA TTTGTGACCTCAGCTTTGGGAATAAAGGATCTTTTGAAGGCCAAA OMIM ID 114835