Entrez gene ID | | 10661 |
Official gene symbol | | KLF1 |
Full name | | Kruppel-like factor 1 (erythroid) |
Aliases | | ,EKLF,INLU, |
Gene summary | | This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.13-p13.12 |
Gene position | | 12998017 - 12995236 Map Viewer |
Gene orientation | | minus |
Gene size | | 2782 bp |
Gene sequence |
| |
OMIM ID | | 600599 |