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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CAPN9 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10753
Official gene symbolCAPN9
Full namecalpain 9
Aliases,GC36,nCL-4,
Gene summaryCalpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q42.11-q42.3
Gene position230883130 - 230937749  Map Viewer
Gene orientationplus
Gene size54620 bp
Gene sequence
OMIM ID606401