Entrez gene ID | | 10785 |
Official gene symbol | | WDR4 |
Full name | | WD repeat domain 4 |
Aliases | | ,TRM82, |
Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.3 |
Gene position | | 44299678 - 44263204 Map Viewer |
Gene orientation | | minus |
Gene size | | 36475 bp |
Gene sequence |
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OMIM ID | | 605924 |
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