Entrez gene ID | | 10855 |
Official gene symbol | | HPSE |
Full name | | heparanase |
Aliases | | ,HPA,HPR1,HPSE1,HSE1, |
Gene summary | | Heparan sulfate proteoglycans (HSPGs) are major components of the basement membrane and extracellular matrix. Heparanases, like HSPE, are endoglycosidases that cleave the heparan sulfate side chain of HSPGs to permit the remodeling of the extracellular matrix for cell movement or the release of bioactive molecules from the extracellular matrix or cell surface (summary by McKenzie et al., 2000 [PubMed 11027606]).[supplied by OMIM] |
Location | | Chromosome: 4 Locus: 4q21.3 |
Gene position | | 84256306 - 84216468 Map Viewer |
Gene orientation | | minus |
Gene size | | 39839 bp |
Gene sequence |
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OMIM ID | | 604724 |
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