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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP24 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10893
Official gene symbolMMP24
Full namematrix metallopeptidase 24 (membrane-inserted)
Aliases,MMP25,MT-MMP5,MT5-MMP,
Gene summaryProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q11.2
Gene position33814539 - 33864804  Map Viewer
Gene orientationplus
Gene size50266 bp
Gene sequence
OMIM ID604871