Entrez gene ID | | 10921 |
Official gene symbol | | RNPS1 |
Full name | | RNA binding protein S1, serine-rich domain |
Aliases | | ,E5.1,MGC117332, |
Gene summary | | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p13.3 |
Gene position | | 2318114 - 2303121 Map Viewer |
Gene orientation | | minus |
Gene size | | 14994 bp |
Gene sequence |
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OMIM ID | | 606447 |
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