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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STIP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10963
Official gene symbolSTIP1
Full namestress-induced-phosphoprotein 1
Aliases,HOP,IEF-SSP-3521,P60,STI1,STI1L,
Gene summarySTIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]
LocationChromosome: 11   Locus: 11q13
Gene position63953587 - 63972020  Map Viewer
Gene orientationplus
Gene size18434 bp
Gene sequence
OMIM ID605063