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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LILRB3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 11025 Official gene symbol LILRB3 Full name leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 Aliases ,CD85A,HL9,ILT5,LIR-3,LIR3,MGC138403,PIRB, Gene summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.4 Gene position 54726959 - 54720147  Map Viewer Gene orientation minus Gene size 6813 bp Gene sequence >LILRB3:complement(26988365..26995177):Length=6813 ATGACAAGAAGGACCCAGCCTCCGAGCGGCCACACCCTGTGTGTCTCTCTGTCCTGCCAG CACTGAGGGCTCATCCCTCTGCAGAGCGCGGGGTCACCGGGAGGAGACGCCATGACGCCC GCCCTCACAGCCCTGCTCTGCCTTGGTGAGATTTCAAGATGGGGAGGGGGAGATCTGAGT CTTGGAGGAACCCCACCCCACACACAAGCCCTGGTCCATCAGGAGACCTCAAAAGCTCAG GAGGCACCCGGGCGGGGACCTGCTCAGGCTTCAGGGCAAATGCCTCACAGGGAACTCTCT TCCAGGGCTGAGTCTGGGCCCCAGGACCCGCGTGCAGGCAGGTGAGTCTGTCCCCAGCTG TCCCAGGTCCCTACTCCTCACTGGGACAGGGGGCCACCCATGGGCAGCTGGGGGAGGAGA CAGTAGTTCTGGGTGACTGATGGGGATGATGGGGAAGTCCTGGGGCTGGGAGCTGGGATC TGAGCGTGGGGATGTCTTGGGATCCAGCCTCTGATTTCCATCTAGGGCCCTTCCCCAAAC CCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGCTGGGGGAGCCCCGTGACCATCTGGT GTCAGGGGAGCCAGGAGGCCCAGGAGTACCGACTGCATAAAGAGGGAAGCCCAGAGCCCT TGGACAGAAATAACCCACTGGAACCCAAGAACAAGGCCAGATTCTCCATCCCATCCATGA CAGAGCACCATGCAGGGAGATACCGCTGCCACTATTACAGCTCTGCAGGCTGGTCAGAGC CCAGCGACCCCCTGGAGATGGTGATGACAGGTGAGAGGACACTCTGGGGTCCCAGCCCCA GGCTCTGCCCTCAGGAAGGGGGTCGGCTCTCAGGGGCGTCTCCCTCTCACAGCCCAGCCC TGGGGATGATGTGGGAGGTGGGAGCCCCATTTAACACGGTGCCTCTTTCTCTCCTAGGAG CCTACAGCAAACCCACCCTCTCAGCCCTGCCCAGCCCTGTGGTGGCCTCAGGGGGGAATA TGACCCTCCGATGTGGCTCACAGAAGGGATATCACCATTTTGTTCTGATGAAGGAAGGAG AACACCAGCTCCCCCGGACCCTGGACTCACAGCAGCTCCACAGTCGGGGGTTCCAGGCCC TGTTCCCTGTGGGCCCCGTGACCCCCAGCCACAGGTGGAGGTTCACATGCTATTACTATT ATACAAACACCCCCTGGGTGTGGTCCCACCCCAGTGACCCCCTGGAGATTCTGCCCTCAG GTGAGGGAGCCACGGCCTTGTCTAACACACTTTCGGGGCAGCTGACAGGTTGTGGGGAGT TTGGCTGGTGACTGAATCTGGAAAGGACCCAGAGTGATGTGTTGAAGGACGGGCTGAAGG CATGAGGGAGACCCCATGGGGAGGCTCTGACATGGGAGGAGGAGCCCTCGACCACGTTCA CCTGGAAGGGGAGGACTCAGGAAGGCATCGGTGTGTTTGCTGTGAGGTCCCAGCTCTCAG GGAGAGGAGGAAAGATCAGGCACAGTGGCCAGGGCTAGGGAGACCCCACTCCTCTGAAAT GACTCCAAGACAGCCCCGGGTGAGAAGGAGGCCCTGGGGTCAGAGACTCAGAGCGTGAGA GACAGTGAGACCTGCAGGGCCAGGACGGGAGAAGGAAGGGGCGTGGGAGGAACCAGCCCT CTCAGTCCTGGCTCCTCTTTCCCTCCAGGCGTGTCTAGGAAGCCCTCCCTCCTGACCCTG CAGGGCCCTGTCCTGGCCCCTGGGCAGAGCCTGACCCTCCAGTGTGGCTCTGATGTCGGC TACAACAGATTTGTTCTGTATAAGGAGGGGGAACGTGACTTCCTCCAGCGCCCTGGCCAG CAGCCCCAGGCTGGGCTCTCCCAGGCCAACTTCACCCTGGGCCCTGTGAGCCCCTCCAAT GGGGGCCAGTACAGGTGCTACGGTGCACACAACCTCTCCTCCGAGTGGTCGGCCCCCAGC GACCCCCTGAACATCCTGATGGCAGGTGAGGAGCCCAGCGGGTTCAGTCAGGGACCCAGG CTCTGCACAGGCCCTGCCGGGGGAGCCCAGGTGGTGATGGCCGGGATGAGGGGTGGGGGT CCCAAGGGAGGGAGAGACAGACAGAGACAGGGGATGGGCGGGGAGGCGAGACTCAGAGAA AACAGGGACAGAGACACTGAGGGTCCCAGGGAGAGGCCTGGGGAGGTGTCAGCTCAGAGC AAGGTGGGGCAGCCCCTCACCCATCCTTCTTCTCTCCAGGACAGATCTATGACACCGTCT CCCTGTCAGCACAGCCGGGCCCCACAGTGGCCTCAGGAGAGAACGTGACCCTGCTGTGTC AGTCATGGTGGCAGTTTGACACTTTCCTTCTGACCAAAGAAGGGGCAGCCCATCCCCCAC TGCGTCTGAGATCAATGTACGGAGCTCATAAGTACCAGGCTGAATTCCCCATGAGTCCTG TGACCTCAGCCCACGCGGGGACCTACAGGTGCTACGGCTCATACAGCTCCAACCCCCACC TGCTGTCTCACCCCAGTGAGCCCCTGGAGCTCGTGGTCTCAGGTGAGGGCGCTGACCCCG TCCTCTCTGAGCTCAAAGGCTCAGCTCAGGCCCAGGCCCCCAGGAGAGCTCTCGGCTGGG ATGGACCGAGGGAGGCTGTGAGGGAGGCTTAGCCAGAGGGCACCCAGCCCTCAGAGGGGA GGAGGCCAACAGGGGTTCTCCTAGGCGTGGCCACCCGTTCTCCCCTGCCTGGCATGCAGA AGGCACCAGGTGGGCAGAGAGATGGTTCCAGGGAATCCACTGGGCGGAAGCAGGAGAGTG GGAGTGGAAGGGTGCACTCCATGGACGGCCCCCGCCCCTCACCCGCCTCCCGTGCTCCTT CCAGGACACTCTGGAGGCTCCAGCCTCCCACCCACAGGGCCGCCCTCCACACCTGGTGAG TCACTGAGGCCTCGTGGGGAGCGCCGCCTCCCCCAGGGCAGTCTGAGTCTCCCAAAGGAT CCCACTCCCCTCCCCTCAAGGACGGGCTTGTGTCCCAGGGGCTCTGAGGCTGGGCTGGTG AAGAGTGGGGGGTCGAGGCAGAGGGAGATGTTGGGGCCCAGCCAGGAGGAGGAGCCGGGC TGATGTGGGGGGCAAGACAGCCCCAGCCTTCACCTCCCTGTCCTGACCCAGGAGGTCCTG AGGACCAGCCCCTTAACCCCCCAGGGTCAGGCCCTCAGAATCGTGAGTGAGGGGCTCTGA GTGGGAGATGGGCGGGGTCCAGGGGAGGCAGGGGTGGGTTCTGTCCTAGGTTCAGGCTCC TCTGGAGGTGGTGATGTGGACAGGCCCCTCCCCTGCCTGGGCCTCAGTTTCTCCAAGTGT AAAGGAGAGAGGCCTGTGGGTGGGAAAGTTCCTTTCAGCTCTGACCCCCAGCTGTGACCT CCTGGGAGAGGAGGCCTCCCAGGGAACCTCCCAGACCCGATTCCACAGGGGCCTGTCCCG TCCCACCTGCAGCAGTGACGGTGACCTGGGGCAGGGGAGGGGAGCAGGGCCGTGGTTCAG GACGGTCAGGCTCTTTCCCTGCAGCTCCGGGTCTCGGCTCTGGTGCAGGAACAAGGGCTG CAGGTCAGACTCCCGGGCTCCCTTCCCAGCTCTGCCGCTTCCTCGCTGGAGGCCTGGGGC AGGCGACTCCCTGCTCTGAGCCTCAGTTTGTGCATCTGTGAAATGGGTTGTACGGGTGGC AATTCCATGTTGCACGACTGCTTGTGAGGGTTGGAGGTCACGAAGGAAAGACCTGGCTCG CGCCTGCACACAGTAGGTGCTCACATCAATGACATCATTCCCACTCCTGACGTCCTCATG TCAAGGTCTGGGAAGATACCTGGAGGTTTTGATTGGGGTCTCGGTGGCCTTCGTCCTGCT GCTCTTCCTCCTCCTCTTCCTCCTCCTCCGACGTCAGCGTCACAGCAAACACAGGACATC TGGTGAGTAGGGAAGCGGGGGACCCATGGGTCGACCGAGGGTGGGCTCAGGGCACCAGCC AGAGGGAACCCAAACACACAGGGGTGTCAGTTTAGAAAACCGGTTCCAGGGGCACGTAAT TTCAATACGCATTTACAAACTTCAGTATTCATGGGAGTTTTTTTCTATCTCATAAAATAT TTGGAACATCCATGCAGGAATATTTTTAGTTTTCCTTCTTTCCCTCAAGTTGCATGTGTA GAATGGGAGTTCTAATGTTCCCAGGGCTGAGACTCTGTCCATCTTCACCCAGACCAGAGA AAGACTGATTTCCAGCGTCCTGCAGGGGCTGCGGAGACAGAGCCCAAGGACAGGGGCCTG CTGAGGAGGTAATTCTGCCCCAAAGACCACAGACTCCCACCCACCACAGCCCATACACTG CCCCTCACACTCCCATGTCCTCCTCCAGGTCCAGCCCAGCTGCTGACGTCCAGGAAGAAA ACCTCTGTAAGAGGAAGAGAGGGGACAAATGGGGGTGCTGGAGAGACAGGAGTCCCAAAA TTTCAGTAGCAACAGGGAGGGGCTGGGAAGGGTCTGGGGCTCCGTGGAAGATGGTCTTGC CCCACACTGTGGGACCTCCCTGCATTCGGTGGCCCCATCTGGGAGCAGGGCAGGGGGCCA GCAGGACTGAGAGGTCTCAGAGAACCAGGAGACGAACCCCTTGCTCTGCCCCAGCAGATG CTGCCGTGAAGGACACACAGTCTGAGGACAGGGTGGAGCTGGACAGTCAGGTGAGATCCC GCCCCGTCCCAGGCACCAAAGGCCTCCTGGTGCCAGATCTAATCCTGCAGGACTTCTCTG TCCTCCTTCCCCCGGCTCTCAGCATCGTCACGGTGGACCCCTCCTTGTCCAGCATGCTGC CTCCCGCCTGCTGTGACCTCACTCTCTTCTGCTGTCCTGGGACCTCGTGGGCCTCCTCCC GGGTCCCCTTCCTGCTCCTCATCCTCTGTTTGGCCGTCTGGTTGTTAGAGCTCTCCCCAG GCCTCAGGAGGATGACGAATAAATGAACCACCTCCGTCCCCTGGGCTCCTCTTCATTCAT TCATCCAGCGAGTGTTCCCAGGGAGCTCACTGTGGATGGGGCTCCCCATGGGAGCTGCAG ACACAGCAGGGAGCAAAGCCGCCCCCGCCTCCTGAGCTCACCTCATGGTGGGAGACAAAA TGCAAATAAATGCATCGTGTCCAGGAGTGCAACGTGCTGTAAGGAACATACACCAGGGAA AGGGCAGAGAGTGTGGGGCAGTGGGGCCAGTCTGAATGGAAGGGGAGGGCTGTCTGCTCA GCTGTCATCTGAGAAGCCTGGACAGAGTGGGGCACATGATCCTCTGATAGACGAGCCCCT GCAGGCAGAGGAAACAGCCGTGCAAAGGCCCCCAGGCAGCAGCGAGCTCTTGCAGGAAGG CCTGTGAGGCTGCAGCCAAATGGGCAAGGTCAGAGTGAGGAGCAGAGGCCAGAACCACAG GGAGGGAGCGGCCAGACCCTCCACGGCCTTAGGGCGTCCCTGAGATTCCATCAGGAAAGG GATGTAATCGGATCACCCCGGGAACAGTGAGGAAAATTGACTCCAGGAGGTCAGGGGGAC TCAAGGACACCCCCCACCACTGTCTCTCTCCAGCAGAGCCCACACGATGAAGACCCCCAG GCAGTGACGTATGCCCCGGTGAAACACTCCAGTCCTAGGAGAGAAATGGCCTCTCCTCCC TCCTCACTGTCTGGGGAATTCCTGGACACAAAGGACAGACAGGTGGAAGAGGACAGGCAG ATGGACACTGAGGTGAGTCCTTTCCTCTCCAGGCCCCCAGGCCTCCCCCACCCCCACCAC GTTCCTTACCTCTCACTCTCCCCCGCTGCAGGCTGCTGCATCTGAAGCCTCCCAGGATGT GACCTACGCCCAGCTGCACAGCTTGACCCTTAGACGGAAGGCAACTGAGCCTCCTCCATC CCAGGAAGGGGAACCTCCAGCTGAGCCCAGCATCTACGCCACTCTGGCCATCCACTAGCC CGGGGGGTACGCAGACCCCACACTCAGCAGAAGGAGACTCAGGACTGCTGAAGGCACGGG AGCTGCCCCCAGTGGACACCAGTGAACCCCAGTCAGCCTGGACCCCTAACACAGACCATG AGGAGACGCTGGGAACTTGTGGGACTCACCTGACTCAAAGATGACTAATATCGTCCCATT TTGGAAATAAAGCAACAGACTTCTCAACAATCAATGAGTTAATAACAAAAAAACAAAAAA CAAAAACAGACGTAAAGGCCGGGTGTGGTACTCAGGAGGCTGAGTGGGGAGGATTCCTTG AACACAAGAAGTTAAGGCTGCTGAGGCTGCAGTGAGCTATGACTGTGCCACTGCACTCCA GCCTGTGTGACAGAGCGAGACCTTGTCTCTAAAAAAAAAAACAGTGAATGTTTTAAACTG AATGATAATGTAAATATTATACATCGAACTTATGACATGGGAAAATTAAGAAGCATAAAT AGGCCGGGCGCGGTGGCTCACGCCTATAATCTCAGCACTTTGGGAGGCTGATGCGGGCGG ATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTA AAAATACAAAAAAATTAGCCGGGCGTGGTGGCGAGTGCCTATAGTCCCAGCTACTCAGGA GGCTGAGGCAGGAGAATGGCATGAGCCCGGGAGGCAGAGCTTGCAGTGAGCTGAGATCGC ACCACTGCACTCCAGCCTGGGCGACAGAGTGAGATTCCGTCTCGAAAAAAAAAAAAAAAG AAAGAAAAAAAATAAAAAAGAAGCATAACCAGG OMIM ID 604820