Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GTF2A1L (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11036
Official gene symbolGTF2A1L
Full namegeneral transcription factor IIA, 1-like
Aliases,ALF,MGC26254,
Gene summaryThe assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p16.3
Gene position48844937 - 48906748  Map Viewer
Gene orientationplus
Gene size61812 bp
Gene sequence
OMIM ID605358