Entrez gene ID | | 11045 |
Official gene symbol | | UPK1A |
Full name | | uroplakin 1A |
Aliases | | ,MGC129751,MGC129752,MGC14388,TSPAN21,UP1A,UPIA,UPKA, |
Gene summary | | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.13 |
Gene position | | 36157715 - 36169367 Map Viewer |
Gene orientation | | plus |
Gene size | | 11653 bp |
Gene sequence |
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OMIM ID | | 611557 |
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